نتایج جستجو برای: m2e

تعداد نتایج: 209  

2016
Francesco Berlanda Scorza Vadim Tsvetnitsky John J. Donnelly

Influenza virus causes acute upper and lower respiratory infections and is the most likely, among known pathogens, to cause a large epidemic in humans. Influenza virus mutates rapidly, enabling it to evade natural and vaccine-induced immunity. Furthermore, influenza viruses can cross from animals to humans, generating novel, potentially pandemic strains. Currently available influenza vaccines i...

2016
Noelia Moreno Ignacio Mena Iván Angulo Yolanda Gómez Elisa Crisci María Montoya José R. Castón Esther Blanco Juan Bárcena

Virus-like particles (VLPs), comprised of viral structural proteins devoid of genetic material, are tunable nanoparticles that can be chemically or genetically engineered, to be used as platforms for multimeric display of foreign antigens. Here, we report the engineering of chimeric VLPs, derived from rabbit hemorrhagic disease virus (RHDV) for presentation of foreign B-cell antigens to the imm...

2017
Ahmed O. Hassan Omar Amen Ekramy E. Sayedahmed Sai V. Vemula Samuel Amoah Ian York Shivaprakash Gangappa Suryaprakash Sambhara Suresh K. Mittal

The emergence of H5, H7, and H9 avian influenza virus subtypes in humans reveals their pandemic potential. Although human-to-human transmission has been limited, the genetic reassortment of the avian and human/porcine influenza viruses or mutations in some of the genes resulting in virus replication in the upper respiratory tract of humans could generate novel pandemic influenza viruses. Curren...

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