The number of edges in a shortest walk (without repetition vertices) from one vertex to another connected graph G is known as the distance between them. For id="M2"> x and an edge id="M3"> e = a b id="M4"> , minimum distances id="M5"> with id="M6"> id="M7"> said be id="M8"> id...

Bu araştırmanın amacı, sağlık sektöründe işlem maliyeti teorisinin (İMT) hangi amaçlar için ne şekilde kullanıldığını belirlemektir. 
 PICOS araştırma sorusu stratejisi, PRISMA protokolü ilkeleri ve akış diyagramı (Follow Diagram) kullanılarak yürütülen araştırmada, 12 Nisan - Mayıs 2022 tarihleri arasında belirlenen arama formülü (farklı anahtar kelimesi kombinasyonu) ile 3 farklı veri ta...

In this paper, we prove that if a space X has point-countable id="M2"> c n -network, then the Pixley-Roy hyperspace id="M3"> P mathvariant="bold">R also id="M4"> -network. If id="M5"> is regular with i...

Elevated expression of plasminogen activator inhibitor-1 (PAI-1) in tumors is associated with a poor prognosis in many cancers. Reduced tumor growth and angiogenesis have also been reported in mice deficient in PAI-1. These results suggest that PAI-1 may be required for efficient angiogenesis and tumor growth. In the present study, we demonstrate that PAI-1 can both enhance and inhibit the grow...

Variability in myosin phosphatase (MP) subunits may provide specificity in signaling pathways that regulate muscle tone. We utilized public databases and computational algorithms to investigate the phylogenetic diversity of MP regulatory (PPP1R12A-C) and inhibitory (PPP1R14A-D) subunits. The comparison of exonic coding sequences and expression data confirmed or refuted the existence of isoforms...

OBJECTIVES The tet(W) gene provides tetracycline resistance to a wide range of anaerobic intestinal and ruminal bacteria, but little is known about the molecular organization of the tet(W) gene. The aim of this study was to gain new insights into the molecular organization of the tet(W) gene in bifidobacteria strains from humans. METHODS A segment of DNA encompassing the whole tet(W) gene and...

Hypoxia is a prominent feature of malignant tumors that are characterized by angiogenesis and vascular hyperpermeability. Vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) has been shown to be up-regulated in the vicinity of necrotic tumor areas, and hypoxia potently induces VPF/VEGF expression in several tumor cell lines in vitro. Here we report that hypoxia-induced VP...

MicroRNAs (miRNAs) are small, noncoding RNA molecules that regulate gene expression at the posttranscriptional level. Originally identified in a variety of organisms ranging from plants to mammals, miRNAs have recently been identified in several viruses. Viral miRNAs may play a role in modulating both viral and host gene expression. Here, we report on the identification and characterization of ...

We show that the recent WMAP data can impose a generous upper bound on the effective masses of electron, muon and tau neutrinos defined in the kinematic measurements: 〈m〉e + 〈m〉μ+ 〈m〉τ = m21 +m22 +m23 < 0.5 eV, or 〈m〉α < 0.71 eV (for α = e, μ, τ). When current neutrino oscillation data are taken into account, we obtain 〈m〉e < 0.24 eV and 〈m〉μ ≈ 〈m〉τ < 0.24 eV. Thus there is no hope to kinematic...