Introduction Molecular imaging aims to detect the presence and spatial distribution of specific biomarkers in tissue. However, for many diseases the detection of these biomarkers must be done at very low concentrations to maximize diagnostic and prognostic value. Due to lack of sensitivity in conventional MRI techniques, exogenous contrast agents (e.g. SPIO, PARACEST) are being widely studied t...

We study a construction of the Mathieu group M12 using a game reminiscent of Loyd’s “15-puzzle”. The elements of M12 are realized as permutations on 12 of the 13 points of the finite projective plane of order 3. There is a natural extension to a “pseudogroup” M13 acting on all 13 points, which exhibits a limited form of sextuple transitivity. Another corollary of the construction is a metric, a...

Spectra with a high signal-to-noise ratio of 50 stars that are just below the main-sequence turno† and are members of M13 are presented. They yield indices for the strength of the CH and the ultraviolet CN band. There is no evidence for a variation in the strength of either feature from star to star in this intermediate-metallicity Galactic globular cluster and, thus, no evidence for primordial...

Second near-infrared (NIR) window light (950-1400 nm) is attractive for in vivo fluorescence imaging due to its deep penetration depth in tissues and low tissue autofluorescence. Here we show genetically engineered multifunctional M13 phage can assemble fluorescent single-walled carbon nanotubes (SWNTs) and ligands for targeted fluorescence imaging of tumors. M13-SWNT probe is detectable in dee...

M13 bacteriophage has been used as a scaffold to organize materials for various applications. Building more complex multiphage devices requires precise control of interactions between the M13 capsid proteins. Toward this end, we engineered a loop structure onto the pIII capsid protein of M13 bacteriophage to enable sortase-mediated labeling reactions for C-terminal display. Combining this with ...

Random amplified polymorphic DNA (RAPD) was used to study the genetic variations among strains from Fusarium sambucinum isolated from wheat in Upper Egypt. Using two different primer (V6 and M13), the used strains showed a high degree of similarities and a distinct RAPD patterns. The dendrogram that constructed based on M13 primers showed that, there is no correlation between isolation sources ...