نتایج جستجو برای: lung hyperinflation
تعداد نتایج: 309153 فیلتر نتایج به سال:
This study compared pulmonary function tests (PFTs) with cardiac, pancreatic and liver iron in 76 thalassemia major (TM) patients. Restrictive lung disease was observed in 16%, hyperinflation in 32% and abnormal diffusing capacity in 3%. While no patients met Global Initiative for Chronic Lung Disease criteria for airways obstruction, there were indicators of small airways disease and air trapp...
Emphysema is one of the pathological manifestations of chronic obstructive pulmonary disease (COPD), which leads to lung hyperinflation, decreased activity of the diaphragm, decreased compliance of the lung, and difficulties in gas exchange. The clinical effect of pharmacological treatment for patients with severe emphysema is limited. In recent years, the emergence of bronchoscopic lung volume...
BACKGROUND In COPD patients, hyperinflation impairs cardiac function. We examined whether lung deflation improves oxygen pulse, a surrogate marker of stroke volume. METHODS In 129 NETT patients with cardiopulmonary exercise testing (CPET) and arterial blood gases (ABG substudy), hyperinflation was assessed with residual volume to total lung capacity ratio (RV/TLC), and cardiac function with o...
The majority of methods for measuring airway mechanics or pulmonary function in small laboratory animals are labor intensive, require specialized equipment and training, and have a low throughput. Hence, there is a need for a more rapid, simpler, userfriendly approach for assessing airway responses in rodent models of human lung diseases. One such method is pulmonary gas trapping or the excised...
Researchers investigating the genetic component of various disease states rely increasingly on murine models. We have developed a ventilator to simplify respiratory research in small animals down to murine size. The new ventilator provides constant-flow inflation and tidal volume delivery independent of respiratory parameter changes. The inclusion of end-inspiratory and end-expiratory pauses si...
BACKGROUND Dyspnea while performing the activities of daily living has been suggested to be a better measurement than peak dyspnea during exercise. Furthermore, the inspiratory capacity (IC) has been shown to be more closely related to exercise tolerance and dyspnea than the FEV1, because dynamic hyperinflation is the main cause of shortness of breath in patients with COPD. However, breathlessn...
Background: Chronic Obstructive Pulmonary Disease (COPD) is one of lung disorders that affect air movement from and out the lung, this can lead to hypoxemia hypercapnia due occurrence respiratory muscle weakness obstruction. As result, it will increase airflow resistance, pulmonary hyperinflation also ventilation perfusion imbalances . One non-pharmacological treatments be given COPD patients i...
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