Objective(s): Abnormal lung cell death including autophagy and apoptosis is the central feature in acute lung injury (ALI). To identify the cellular mechanisms and the chronology by which different types of lung cell death are activated during lipopolysaccharide (LPS)-induced ALI, we decided to evaluate autophagy (by LC3-II and autophagosome) and apoptosis (by caspase-3) at different time point...

Background and aims: Lung cancer is the leading cause of cancer death worldwide. There are no recent data on the lung cancer prevalence in Lebanon, and the available data are based on prediction. Thus, this study aimed to determine the incidence rate of lung cancer during 2014, among patients who were newly diagnosed at Lebanese teaching hospitals. In addition, the study attempted to identify t...

introduction: pulmonary involvement secondary to systemic sclerosis (ssc) is the major cause of morbidity and mortality in ssc patients. we designed this study to determine the correlation of important lung function parameters with lung high resolution ct (hrct) scan findings.materials and methods: thirty–two consecutive diffuse ssc patients with pulmonary fibrosis were enrolled in this cross-s...

dr.mirsadraei and colleagues performed an interesting study about the lung hrct findings in chemical warfare patients who suffering from long-term pulmonary complications. they found that air trapping and mosaic attenuation were the most common lung hrct findings. also they divided patients in different clinical entities according to the lung hrct findings (bronchiolitis oblitrans, pulmonary fi...

introduction lung herniation following blunt chest trauma is extremely rare and only a few hundred cases of this pathology have been reported in the english language medical literature. this type of lung hernia is divided into intercostal, parasternal, or supraclavicular subtypes based on the exact location of the chest wall defect. traumatic intercostal lung hernia is even more uncommon. delay...

transforming growth factor-beta (tgf-β) is one of the most important cytokines implicated in growth, differentiation, repair and also the pathogenesis of the lung fibrosis by its stimulatory effect on extracellular matrix deposition. pulmonary epithelial cells are considered as a source of tgf-β in lung. substance p (sp), as a neuroimmunomodulator has elevated levels in inflamed airways and alt...

Introduction: Treatment of lung diseases is one of the major healthcare challenges. Ferulic acid (FA), a phenolic compound with well-established antioxidant and anti-inflammatory properties, has shown promising therapeutic potential against the pulmonary disorders; however, low bioavailability may negatively affect its efficiency. This, prompted us to incorporate FA into the nanostructured ...

Background: Chest CT is a commonly used examination for the diagnosis of lung diseases, but a breast within the scanned field is nearly never the organ of interest.Objective: The purpose of this study is to compare the female breast and lung doses using split and standard protocols in chest CT scanning.Materials and Methods: The sliced chest and breast female phantoms were used. CT exams were p...

the clinical management of pulmonary embolism and deep venous thrombosis of the legs are similar and requires prolonged anticoagulation therapy. the standard diagnostic approach in patients suspected of pulmonary embolism is ventilation-perfusion (v/q) lung scan and compression ultrasonography to detect deep venous thrombosis. this retrospective study analyzed the role of v/q lung scan and comp...