OBJECTIVE To investigate the efficacy of brachytherapy for patients with localized prostate cancer and the influence factors. METHODS There were 61 patients with localized prostate cancer were treated with brachytherapy between April 2001 and March 2011 in Department of Urology, Peking University First Hospital, including 11 patients who received combined external beam radiotherapy. The mean ...

OBJECTIVES To better identify factors affecting prostate-specific antigen (PSA) level elevation after radical prostatectomy alone in men with clinical Stage T1-2 prostate cancer, we have reviewed our experience in the PSA era with 337 cases. The identification of these factors permits better understanding of the impact of case selection on treatment outcome in prostate cancer. METHODS The cha...

PURPOSE To develop a prognostic model and nomogram using baseline clinical variables to predict death among men with metastatic hormone-refractory prostate cancer (HRPC). EXPERIMENTAL DESIGN TAX327 was a clinical trial that randomized 1,006 men with metastatic HRPC to receive every three week or weekly docetaxel or mitoxantrone, each with prednisone. We developed a multivariate Cox model and ...

PURPOSE Active surveillance (AS) is an option for the initial management of early-stage prostate cancer. Current risk stratification schema identify patients with low-risk disease who are presumed to be most suitable for AS. However, some men with higher risk disease also elect AS; outcomes for such men have not been widely reported. PATIENTS AND METHODS Men managed with AS at University of C...

reservoir permeability is a critical parameter for characterization of the hydrocarbon reservoirs. in fact, determination of permeability is a crucial task in reserve estimation, production and development. traditional methods for permeability prediction are well log and core data analysis which are very expensive and time-consuming. well log data is an alternative approach for prediction of pe...

BACKGROUND Patients with locally advanced and high-risk prostate cancer (LAPC) are prone to experience biochemical recurrence despite radical prostatectomy (RP). We evaluated feasibility, safety and activity of a neoadjuvant chemohormonal therapy (NCHT) with 3-weekly full dose docetaxel and complete androgen blockade (CAB) in locally advanced and high-risk prostate cancer patients (LAPC) underg...

Reservoir permeability is a critical parameter for characterization of the hydrocarbon reservoirs. In fact, determination of permeability is a crucial task in reserve estimation, production and development. Traditional methods for permeability prediction are well log and core data analysis which are very expensive and time-consuming. Well log data is an alternative approach for prediction of pe...

OBJECTIVE Early identification of patients unlikely to achieve good long-term disease control with anti-tumor necrosis factor therapy in axial spondyloarthritis (SpA) and psoriatic arthritis (PsA) is important for physicians following treat-to-target recommendations. Here we assess associations between disease activity or clinical response during the first 12 weeks of treatment and attainment o...