We use the Malliavin integration by parts formula in order to provide a family of representations of the joint density (which does not involve Dirac measures) of (Xθ, Xθ+δ), where X is a d-dimensional Markov diffusion (d ≥ 1), θ > 0 and δ > 0. Following [5], the different representations are determined by a pair of localizing functions. We discuss the problem of variance reduction within the fa...

The combinatorial action of co-localizing chromatin modifications and regulators determines chromatin structure and function. However, identifying co-localizing chromatin features in a high-throughput manner remains a technical challenge. Here we describe a novel reChIP-seq approach and tailored bioinformatic analysis tool, normR that allows for the sequential enrichment and detection of co-loc...

Given a multi-dimensional Markov diffusion X, the Malliavin integration by parts formula provides a family of representations of the conditional expectation E[g(X2)|X1]. The different representations are determined by some localizing functions. We discuss the problem of variance reduction within this family. We characterize an exponential function as the unique integratedvariance minimizer amon...

Lung disorders or injury can result in changes in the production of lung sounds both spectrally and regionally. Localizing these lung sounds can provide information to the extent and location of the disorder. Difference in arrival times at a set of sensors and triangulation were previously proposed for acoustic imaging of the chest. We propose two algorithms for acoustic imaging using a set of ...

Both 3H-labeled and unlabeled hematoporphyrin derivative (HPD) were analyzed by high-pressure liquid chromatography (HPLC) and gel permeation chromatography. Four main compo nents were isolated by HPLC, and two were isolated by gel permeation chromatography. The tumor-localizing ability of each component was tested and compared to that of 67Gaand 3H20 by injection in mice bearing Lewis lung car...

Both 3H-labeled and unlabeled hematoporphyrin derivative (HPD) were analyzed by high-pressure liquid chromatography (HPLC) and gel permeation chromatography. Four main components were isolated by HPLC, and two were isolated by gel permeation chromatography. The tumor-localizing ability of each component was tested and compared to that of 67Ga and 3H2O by injection in mice bearing Lewis lung car...

We revisit the notion of ontology localization, propose a new definition and clearly specify the layers of an ontology that can be affected by the process of localizing it. We also work out a number of dimensions that allow to characterize the type of ontology localization performed and to predict the layers that will be affected. Overall our aim is to contribute to a better understanding of th...

The reliability and accuracy of point-based image registration strongly depends on the selection of suitable landmarks and on the precision of localizing theses landmarks in images. In this contribution, we consider the problem of landmark extraction for the purpose of aerial image registration. We suggest to use a specific type of circular landmarks and introduce a model-based approach for loc...

Efficient detection of integrity violations is crucial for the reliability of both data at rest and data in transit. While ideally one would want to always find all changes in the input data, in practice this capability may be expensive, and one may be content with localizing or finding a superset of any changes. Corruption-localizing hashing [5] is a cryptographic primitive that enhances colli...

In this paper we explore how two enactments of HIV – the UN’s AIDS Clock and clinical trials for an HIV biomedical prevention technology or pre-exposure prophylaxis (PrEP) entail particular globalizing and localizing dynamics. Drawing on Latour’s and Whitehead’s concept of proposition, and Serres’ call for a philosophy of prepositions, we use the composite notion of pre/propostitons to trace th...