background and aims: recurrent aphthous stomatitis (ras) is one of the most common ulcerative diseases of the oral mucosa. definitive etiology of ras has not been conclusively established. there is no certain treatment for aphthous but some drugs such as steroid are commonly used for treatment of ras. regarding the effect of zinc on healing process of epithelial layer and cell division, in this...

Ferreira JC, Bacurau AV, Evangelista FS, Coelho MA, Oliveira EM, Casarini DE, Krieger JE, Brum PC. The role of local and systemic renin angiotensin system activation in a genetic model of sympathetic hyperactivity-induced heart failure in mice. Am J Physiol Regul Integr Comp Physiol 294: R26–R32, 2008. First published October 31, 2007; doi:10.1152/ajpregu.00424.2007.—Sympathetic hyperactivity (...

Background and purpose: Metadiscourse markers (MDMs) play a significant role in academic witting. They act as a bridge between writers and readers and make a text more understandable. Therefore, this study aimed at investigating the use of MDMs in introduction, methods, results, and discussion (IMRaD) sections of English medical research articles (RAs) published in Iranian and American ISI jour...

More than 100 years ago, mast cells were discovered and named by Paul Ehrlich who was the first to recognize this well-fed appearing cell loaded with huge cytoplasmic granules in various tissues [1]. Mast cells derive from CD34þ multipotent bone marrow progenitor cells which circulate in small numbers in the blood as basophilic leucocytes, and enter the mucosal surfaces and connective tissue co...

Background and objectives: Recurrent aphthous stomatitis (RAS) is a painful ulcerative lesion and its incidence is 20% in the society. Myrtus communis (myrtex) has been effective in the treatment of RAS. In this study, two different concentrations (2.5% versus 5%) of myrtex extract were evaluated to discover the most effective concentration for the treatment of RAS. Methods: In this randomized...

statement of problem: recurrent aphthous stomatitis (ras) is one of the most common inflammatory diseases encountered in dental practice, but the precise etiology and pathogenesis of the disease is not fully understood. vascular endothelial growth factor (vegf) is a multifunctional angiogenic cytokine involved in angiogenesis and wound healing. there is evidence that vegf could play an importan...

The local renin-angiotensin system (RAS) has been reported to have an important role in the pathogenesis and progression of metabolic bone diseases, including osteoarthritis (OA). Aliskiren is the first in a new class of orally effective direct renin inhibitors and is approved for the treatment of hypertension in humans. However, its efficacy in patients with OA is unknown. A rat model of OA wa...

The aim of this study was to investigate changes in immunoreactivity of Ras and Raf-1 in lung epithelial cells of rats exposed to carcinogen NNK after swimming training. 50 Wistar rats were randomly divided into five groups: control, training, training + NNK, NNK and sham. NNK-induced groups received NNK Subcutaneously once a week at a dose of 12/5 mg per kg body weight for 12 weeks. The exerci...