Signet ring cell (SRC) carcinoma is a unique subtype of adenocarcinoma; however, the clinicopathological profiles of SRCs in breast carcinoma are yet to be determined. Here, we investigated cyto-histological findings of 11 breast carcinoma cases with SRCs comprising more than 20% of the tumor cells; invasive ductal carcinoma (IDC) (n=4), invasive lobular carcinoma (ILC) (n=4), pleomorphic lobul...

The diagnosis of basosquamous cell carcinoma is controversial. A review of cases of basal cell carcinoma showed 23 cases that had conspicuous areas of squamous cell carcinoma. This was distinguished from squamous differentiation and keratotic basal cell carcinoma by a comparative study of 40 cases of compact lobular and 40 cases of keratotic basal cell carcinoma. Areas of intermediate tumour di...

to the editor: The article on the risk of cancer in patients with benign breast disease by Hartmann et al. (July 21 issue) 1 contains some questionable assumptions. “Atypical ductal hyperplasia” and “lobular hyperplasia,” shown in Figure 1E and Figure 1F of the article, do not belong in the category of benign breast disease. Experienced pathologists know that the differentiation of the so-calle...

Breast carcinoma; Modiied Radical Mastectomy; Ductal carcinoma; Medullary features; Lobular; Mucinous. Background: Carcinoma of breast has become the major public health problem among females in developing as well as developed countries. In Nepal it comprises 6% of total cancers cases and often diagnosed at advanced stage. Surgical removal or modiied radical mastectomy (MRM) is the most commonl...

Pulmonary tuberculosis (TB) and lung cancer are both common diseases with poor prognosis high mortality worldwide. The coexistence of the two has rarely been reported while their relationship noted. Here we describe a patient diagnosed TB squamous cell carcinoma in single lesion. had cough for four months polypnea months, smoking history over 40 years. Chest computed tomography (CT) showed lobu...

A growing body of evidence support the association between the use of hormone replacement therapy (HRT) and a higher risk of both invasive lobular carcinoma (ILC) and invasive ductal-lobular mixed carcinoma (IDLC). Overall biological and clinical features of ILC entail a more cautious diagnostic and therapeutic approach as compared with invasive ductal carcinoma (IDC). ILCs are more frequently ...