We have recently developed some simple continuum models of static granular media which display “fragile” behaviour: they predict that the medium is unable to support certain types of infinitesimal load (which we call “incompatible” loads) without plastic rearrangement. We argue that a fragile description may be appropriate when the mechanical integrity of the medium arises adaptively, in respon...

We conducted a replication study of the 2 genetic variants, rs11754661 and rs2073067, in MTHFD1L that have been recently reported to be associated with late-onset Alzheimer's disease (LOAD) in a genome-wide study in Caucasians. The associations were evaluated in a case-control sample comprising 1,189 Northern Han-Chinese individuals. The rs11754661 polymorphism is associated with LOAD (OR = 1.7...

The accurate cooling load prediction of ice storage system is the basis and foundation for optimization control. In order to implement the optimal control of ice storage system, the accurate cooling load prediction is very important. This paper proposes that the SVM (support vector machine) combined with rough set is used for the load prediction of ice storage system. The simulation results pro...

We describe a case of a patient assisted by extracorporeal life support, in which we obtained the dynamic filling index, a measure for venous volume during extracorporeal life support, and used this index to assess cardiac load-responsiveness during acute reloading. While reloading, the obtained findings on cardiac pump function by the dynamic filling index were supported by trans-esophageal ec...

A low dropout voltage regulator with small output voltage variations and the ability of wide load current range support is proposed in this paper. In this LDO structure, a recycling folded cascode operational transconductance amplifier is used as an error amplifier, which has high transconductance and therefore high power efficiency. The designed LDO is simulated in 0.18 μm CMOS standard techno...

In order to address the needs of data visualization software we propose that e-Science should support the dynamic load balancing of data integration agents and that this mechanism could be supported by grids of collaborating computing infrastructures. Examples will be given of a service tailored along these lines to support visualization client software. The new service will better support the ...

Vertical load was applied uniformly over the entire top surface of the plate, and the load was increased in increments. For each load increment, the equilibrium state of the problem was determined. Because of the continuously hardening postyield behavior of Titanium Grade 7, equilibrium could be achieved for any vertical load. However, at a certain load level, the region of the plate between th...

The ever increasing automation and manning reductions in process control result in enormous fluctuations of the operators cognitive task load. A possible solution in keeping operator load and performance at an adequate level over time, is adaptive support. Our paper combines recently developed support functions into a new adaptive support framework. It shows which information of operator, task,...

The following article investigates nonlinear symmetric buckling of moderately thick circular Nano plates with an orthotropic property under uniform radial compressive in-plane mechanical load. Taking into account Eringen nonlocal elasticity theory, principle of virtual work, first order shear deformation plate theory (FSDT) and nonlinear Von-Karman strains, the governing equations are obtained ...