In the excised canine left ventricle, the end-systolic pressure-volume relationship (ESPVR) has been shown to be approximately linear over the working range of loading conditions when coronary arterial pressure (CAP) is maintained constant, independent of loading conditions. To investigate the ESPVR under the more intact physiological condition in which the CAP varies with loading on the left v...

The effect of long-term oral sodium loading on blood pressure and on stress-induced cardiovascular response was studied in normotensive and marginally hypertensive young adults. The 121 subjects, 18-23 years old, included 38 whites and 83 blacks. Blood pressure and heart rate response to the stress of mental arithmetic was measured before and after 14 days of sodium load, which consisted of 10 ...

The elastic buckling of shell structures such as spherical shells subject to external pressure and cylindrical shells loaded in axial compression is highly sensitive to imperfections and often catastrophic. Recent studies of spherical shells have provided accurate quantitative results for the relation between the buckling pressure and the amplitude and shape of geometric imperfections and, addi...

Mean arterial blood pressure, heart rate, and cardiac output were measured during continuous graded exercise (5.5 km/hr; 0, 7, 14, and 21% grades) in conscious dogs, under each of the following four conditions: (1) baroreceptors intact, (2) chronic aortic arch denervation, (3) chronic aortic arch denervation and surgical preparation of the carotid sinuses for later reversible vascular isolation...

Modern processors and compilers hide long memory latencies through non-blocking loads or explicit software prefetching instructions. Unfortunately , each mechanism has potential drawbacks. Non-blocking loads can signiicantly increase register pressure by extending the lifetimes of loads. Software prefetching increases the number of memory instructions in the loop body. For a loop whose executio...

This paper deals with torque reduction control for an electro-pneumatic hybrid vertical positioning system composed of a servomotor a pneumatic and a mechanical driving sub-system. The servomotor, coupled with a ball screw connected to the load by nut, enables to position a load vertically. The servomotor with small capacity, as well as energy saving, is required for cost down. To realize its s...

BACKGROUND Peak early-diastolic mitral annulus velocity (e') by tissue Doppler imaging has been introduced as a clinical marker of diastolic function. This study investigates whether lengthening load (early-diastolic load) and restoring forces are determinants of e' in addition to rate of left ventricular (LV) relaxation. METHODS AND RESULTS In 10 anesthetized dogs, we measured e' by sonomicr...

The various process parameters affecting the quality characteristics of the shock absorber during the process were identified using the Ishikawa diagram and by failure mode and effect analysis. The identified process parameters are welding process parameters (squeeze, heat control, wheel speed, and air pressure), damper sealing process parameters (load, hydraulic pressure, air pressure, and ...