Restricted Maximum Likelihood (REML) is the most recommended approach for fitting a Linear Mixed Model (LMM) nowadays. Yet, as ML, REML suffers drawback that it performs such by assuming normality both random effects and residual errors, dubious assumption many real data sets. Now, there have been several attempts at trying to justify use of likelihood equations outside Gaussian world, with var...

Abstract Background Little is known about how disease co-occurrences with common mental disorders (CMD) associate social integration in young refugees. We identify diagnostic groups associated labor market marginalization (LMM) refugees and Swedish-born CMD determine whether multimorbidity LMM CMD. Methods This longitudinal registry-based study included adults aged 20-25 years followed from 201...

Mechanisms involved in melanoma invasiveness and metastasis are essential to understanding the behavior of this aggressive melanocytic skin cancer. The epithelial-mesenchymal transition (EMT) is considered fundamental for overcoming the in situ stage of melanoma and its proliferation beyond the basal membrane. Matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) are key molecule...

A fundamental problem in wireless sensor networks is to maximize network lifetime under given energy constraints. In this paper, we study the network lifetime problem by considering not only maximizing the time until the first node fails, but also maximizing the lifetimes for all the nodes in the network, which we define as the Lexicographic Max-Min (LMM) node lifetime problem. The main contrib...

Serum and urine samples were collected from 33 NCC patients before the albendazole treatment, 3-6 and 12 months PT. At 3 months PT, 24 (72.7%) patients had no detectable CT/MRI lesions and 9 (27.2%) patients had persistent lesions. Antibody response to crude soluble extract (CSE), excretory secretory (ES), and lower molecular mass (LMM) (10-30 KDa) antigenic fraction of T. solium cysticerci was...

Several tumor-derived factors have been implicated in dendritic cell (DC) dysfunction in cancer patients. α-fetoprotein (AFP) is an oncofetal Ag that is highly expressed in abnormalities of prenatal development and several epithelial cancers, including hepatocellular carcinoma (HCC). In HCC patients exhibiting high levels of serum AFP, we observed a lower ratio of myeloid/plasmacytoid circulati...

OBJECTIVE To investigate the relationship of muscle mass and muscle function with age. METHODS AND STUDY DESIGN The study including 415 participants (aged 60-99 years). Upper (UMM) and lower (LMM) limbs muscle mass and whole body fat free mass (FFM) were measured by bioelectrical impedance analysis. The appendicular skeletal muscle mass (ASM) index (ASM/height2) was calculated. Muscle functio...

For the efficient numerical solution of indefinite linear systems arising from curl conforming edge element approximations of the time-harmonic Maxwell equation, we consider local multigrid methods (LMM) on adaptively refined meshes. The edge element discretization is done by the lowest order edge elements of Nédélec's first family. The LMM features local hybrid Hiptmair smoothers of Jacobi and...

The current study focused on how engaging in media multitasking (MMT) and the experience of everyday cognitive failures impact on the individual’s engagement in risky cybersecurity behaviors (RCsB). In total, 144 participants (32 males, 112 females) completed an online survey. The age range for participants was 18 to 43 years (M= 20.63, SD= 4.04). Participants completed three scales which inclu...