The aim of the study was to define biological subtypes of breast cancer that have the propensity to metastasize to the leptomeninges and to assess factors influencing survival from detection of leptomeningeal metastatis (LM). One hundred and eighteen consecutive breast cancer patients with LM were treated in one institution, between the years 1999 and 2009; 40.5 % of patients had triple-negativ...

A two-stage latent prosody model-language model (LPM-LM)-based approach is proposed to identify two Mandarin accent types spoken by native speakers in Mainland China and Taiwan. The frontend LPM tokenizes and jointly models the affections of speaker, tone and prosody state of an utterance. The backend LM takes the decoded prosody state sequences and builds n-grams to model the prosodic differen...

We propose a novel approach to crosslingual language model (LM) adaptation based on bilingual Latent Semantic Analysis (bLSA). A bLSA model is introduced which enables latent topic distributions to be efficiently transferred across languages by enforcing a one-to-one topic correspondence during training. Using the proposed bLSA framework crosslingual LM adaptation can be performed by, first, in...

OBJECTIVE The objective of this study was to evaluate, in an international multicenter phase III trial, the accuracy, use, and morbidity of intraoperative lymphatic mapping and sentinel node biopsy (LM/SNB) for staging the regional nodal basin of patients with early-stage melanoma. SUMMARY BACKGROUND DATA Since our introduction of LM/SNB in 1990, this technique has been widely adopted and has...

OBJECTIVES The purpose of this study was to evaluate the left main (LM) coronary artery anatomy using three-dimensional (3D) quantitative coronary angiography (QCA) software as compared to intravascular ultrasound (IVUS). BACKGROUND Percutaneous intervention of the LM coronary artery is becoming more common in selected patients with LM coronary artery disease (CAD). Quantification of LM CAD b...

Deep neural networks have become the state-of-the-art models in numerous machine learning tasks. However, general guidance to network architecture design is still missing. In our work, we bridge deep neural network design with numerical differential equations. We show that many effective networks, such as ResNet, PolyNet, FractalNet and RevNet, can be interpreted as different numerical discreti...

Accuracy and repeatability of live-animal ultrasound measures, and the relationships of these measures with subprimal yields and carcass value, were investigated using data from 172 wethers. Wethers were F(1) progeny from the mating of 4 terminal sire breeds to Rambouillet ewes and were finished in a feedlot to a mean BW of 62.9 kg (SD = 9.5 kg). Before transport to slaughter, LM area, LM depth...

INTRODUCTION Ultrasound-guided (UG) technique is the recommended procedure for central venous catheterization (CVC). However, as ultrasound may not be available in emergency situations, guidelines also propose that physicians remain skilled in landmark (LM) placement. We conducted this prospective observational study to determine the learning curve of the LM technique in residents only learning...

BACKGROUND Body composition and resting energy expenditure (REE) have not been examined longitudinally during puberty. OBJECTIVE The purpose of this longitudinal study was to examine the influence of pubertal maturation on REE relative to body composition in African American and white children. DESIGN The study included 92 white and 64 African American children (mean age at baseline: 8.3 an...

(2015) Dendritic distributions of I h channels in experimentally-derived multi-compartment models of oriens-lacunosum/moleculare (O-LM) hippocampal interneurons. The O-LM cell type mediates feedback inhibition onto hippocampal pyramidal cells and gates information flow in the CA1. Its functions depend on the presence of voltage-gated channels (VGCs), which affect its integrative properties and ...