On examination.?There was puffiness of the face and slight oedema around the ankles, marked pallor and slight icteric tinge of the conjunctivae. Tongue very pale and smooth. Temperature 99.6?F. Pulse 100 and respiration 24 per minute. B.P. 110/60 mm. of Hg. A few scattered rhonchi were audible in both lungs and no abnormality was detected in the heart. Spleen and liver were both palpable. In th...

1. A sepoy, aged 30, had fever for 3 days prior to admission and was passing diarrhceic stools. On admission, the patient was of slow disposition, with a slightly toxsemic look; tongne furred; respiration 20; pulse 32; distinct tenderness over the liver region especially over the gall-bladder. No other abnormality found on clinical examination. The patient had two bouts of diarrhoea lasting two...

Prolonged or permanent impairment of liver function is now known to occur in a variable proportion of patients following an attack of infectious hepatitis or serum jaundice (1-11). However, the incidence of this chronic hepatic disease is not well established because of the difficulty in correlating symptomatology with the available liver function tests or with liver biopsy (12-15). Of the mean...

Mammalian sirtuin 1 (SIRT1) may control fatty acid homeostasis in liver. However, this possibility and underlying mechanism remain to be established. In this study, we addressed the issues by examining the metabolic phenotypes of SIRT1 heterozygous knockout (SIRT1(+/-)) mice. The study was conducted in the mice on three different diets including a low-fat diet (5% fat wt/wt), mediate-fat diet (...

Liver Cancer is one in every of the speediest growing cancer in the world. The early detection and diagnosing of liver tumor growth is vital for the hindrance of liver tumor growth. More than 30% of cancer deaths may be prevented by avoiding risk factor, early detection, accurate diagnosis, and effective treatment. Segmentation of liver from medical images from the abdominal space is vital for ...

Approximately one in 10 Canadians has at least one abnormal liver biochemical test on routine screening. Although in the majority of these individuals the abnormality reflects a benign liver condition such as Gilbert’s syndrome or enzyme induction from recent alcohol consumption, a subgroup will have progressive and potentially life-threatening liver disease for which therapeutic interventions ...

We determined the associations of HIV infection/CD4 count with markers of hepatocellular damage [elevated aspartate aminotransferase (AST) and alanine aminotransferase (ALT)] and liver synthetic function (decreased albumin) in HIV-infected (HIV(+)) antiretroviral therapy (ART)-naive and uninfected (HIV(-)) Rwandan women. In 2005, 710 HIV(+) ART-naive and 226 HIV(-) women enrolled in the Rwanda ...

BACKGROUND Chromosomal abnormality is a common cause of congenital anomalies, psychiatric disorders, and mental retardation. However, the double trisomy 48,XXX,+18 is a rare chromosome abnormality. METHODS Case report and literature review. RESULTS A 7-hour-old girl presented to our unit because of poor response after birth. She presented with multiple dysmorphic features, including small f...

Obesity with associated comorbidities is currently a worldwide epidemic and among the most challenging health conditions in the 21st century. A major metabolic consequence of obesity is insulin resistance which underlies the pathogenesis of the metabolic syndrome. Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of obesity and metabolic syndrome. It comprises a disease spec...