Solubilized proteins Detergent-solubilization of membrane proteins has proved to be a successful approach in many cases. Both ionic and nonionic detergents have been used: the choice of detergent may be crucial for retaining protein activity. Generally, detergents should be used at concentrations above their critical micelle concentration (CMC). Micelles formed above the CMC mimic a membrane en...

Submit Manuscript | http://medcraveonline.com J Anal Pharm Res 2015, 1(1): 00001 in terms of dissolution but the non-traditional formulation approaches can lead to a significant increase in dissolution and solubility particularly required for drugs applied in medium to higher dosages [3]. Such dosages’ requirements go along with the necessity to evaluate other formulation technologies for enhan...

The synthesis of medium-chain carboxylates (MCCs) from waste-activated sludge (WAS) upgrading has received considerable attention. However, limited research been conducted on the effects CeO2 nanoparticles (NPs) this process. This study showed that 1 mg/g−TS NPs improved solubilization WAS, resulting in higher production MCCs. At 5 mg/g−TS, weakly inhibited 3 biological steps. Despite this, the...

PAH removal with surfactant enhanced washing was investigated through a series of laboratory tests to examine the effect of stirring speed, washing time, surfactant concentration, liquid/solid ratio, temperature, and on-and-off mode. The first four factors show significant influence on the PAH removal while the latter two do not. Total removal ratio and a new proposed parameter, solubilization ...

The purpose of this work is to provide a mechanistic understanding of the dissolution behavior of cocrystals under the influence of ionization and micellar solubilization. Mass transport models were developed by applying Fick's law of diffusion to dissolution with simultaneous chemical reactions in the hydrodynamic boundary layer adjacent to the dissolving cocrystal surface to predict the pH at...

Solubilization and ion-exchange chromatography of plasma membrane proteins obtained from bean (Phaseolus vulgaris L.) seedlings resulted in a single NAD(P)H-O,--synthase protein peak. This enzyme showed a high preference toward NADPH as a substrate (reaction rate, 27.4 nmol O,produced min-' mg-' protein), whereas NADH reactions ranged from O to maximally 15% of the NADPH reactions. l h e protei...

The bio-solubilization of Jordan phosphorite by the phosphate-solubilizing fungus Aspergillus niger has been investigated. The effect of the phosphate concentration in the liquid medium, the duration of biodecomposition, titratable acidity and the effect of preliminary mechanical activation on the process of dissolution have been studied. The investigations indicate that almost complete extract...