Oxygen-derived free radicals such as hydroxyl and hydroperoxyl species have been demonstrated to oxidize membrane lipid components, mainly phospholipids, leading to lipid peroxidation. Membrane phospholipids containing polyunsaturated fatty acids are predominantly susceptible to peroxidation. Free radical catalyzed peroxidation of long chain polyunsaturated acids (LCPUFAs) such as arachidonic a...

Casein and whey proteins with and without heat treatment were obtained of whole milk and four commercial milks in Ecuador, and were hydrolyzed. Then, their capacity to inhibit the lipid peroxidation using the TBARS method was evaluated at concentrations of 0.02, 0.04, 0.2, and, 0.4 mg/mL. Native and heated hydrolysates of milk proteins present high inhibitions of lipid peroxidation with a dose ...

Antioxidative effect of aqueous extract of rhizome of Ginger (Zinziber officinale) was examined on p-hydroxybenzoic acid (paraben) induced lipid peroxidation. Addition of paraben (25-150 microg/mL) to liver and kidney homogenates significantly increases H2O2 induced lipid peroxidation in vitro. Effect was dose dependent up to 100 microg/mL concentration. An addition of aqueous extract of ginger...

BACKGROUND Halothane is extensively (approximately 50%) metabolized in humans and undergoes both oxidative and reductive cytochrome P450-catalyzed hepatic biotransformation. Halothane is reduced under low oxygen tensions by CYP2A6 and CYP3A4 in human liver microsome to an unstable free radical, and then to the volatile metabolites chlorodifluoroethene (CDE) and chlorotrifluoroethane (CTE). The ...

Effect of occupation on haematological factors, lipid peroxidation and antioxidants' status was studied in masons and compared with normal subjects. Red blood corpuscles (RBC), haemoglobin (Hb), Vitamin C, Vitamin E, beta-carotene levels and glutathione peroxidase (GSHPx), superoxide dismutase (SOD) and catalase (CAT) activities decreased. Thiobarbituric acid reacting substances (TBARS) level i...

Reactive oxygen species formed as a response to various abiotic and biotic stresses cause an oxidative damage of cellular component such are lipids, proteins and nucleic acids. Lipid peroxidation is considered as one of the major processes responsible for the oxidative damage of the polyunsaturated fatty acid in the cell membranes. Various methods such as a loss of polyunsaturated fatty acids, ...

processes are involved in the development of diabetes. Abstract The lipid profile levels were found to be elevated in T2DM diabetic patients. The study was designed to find out the correlation between lipid peroxidation, lipid profile and T2DM. Degree of lipid peroxidation was measured in terms of malondialdehyde (MDA) along with lipid profile and blood glucose in diabetes mellitus. Totally 50 ...