BACKGROUND The bulk of cardiovascular disease risk is not explained by traditional risk factors. Recent advances in mass spectrometry allow the identification and quantification of hundreds of lipid species. Molecular lipid profiling by mass spectrometry may improve cardiovascular risk prediction. METHODS AND RESULTS Lipids were extracted from 685 plasma samples of the prospective population-...

Objective: Vitamin E acetate has antioxidant activity that can prevent premature aging of the skin, but it is highly lipophilic (log p±12.2) and potentially degraded. To overcome permeability stability problems, vitamin needs to be developed in Nanostructured Lipid Carrier (NLC), a nano-delivery system based on solid lipid liquid stabilized by surfactants as colloidal system.
 Methods: The...

Solid Lipid Nanoparticles (SLN) have been prepared by high-pressure homogenization and optimized in order to protect ferulic acid from Ferula assa-foetida L. extract. The influence of lipid surfactant concentration on the mean particle size (Z-Ave), polydispersity index (PDI), zeta potential (ZP) SLN was analyzed. In addition, other parameters for preparation acid-loaded nanoparticles, such as ...

Introduction: Cardiovascular diseases are the leading cause of mortality in India. The important factor associated is dyslipidemia. A strong relationship has been seen in epidemiological studies between cholesterol and cardiovascular disease. The present study was planned to analyse cord blood lipid profile, apolipoproteins and atherogenic index and to see their relationship with birth weight. ...

background: soymilk replacement in the diet might have beneficial effects on inflammation and cardiovascular risk factors for non-menopausal overweight and obese female adults. we evaluated the effects of soymilk compared to cow's milk on inflammation and cardiovascular risk factors among overweight and obese female adults. materials and methods: this was a cross-over randomized clinical trial ...

Background Severe oxidative stress has been reported in tuberculosis [TB] patients. There are no previous reports regarding oxidative stress index and supplementation of antioxidants in TB. The objective of this study was to assess the antioxidant status, lipid peroxidation and oxidative stress index in TB patients. Also to assess the antioxidant supplementation with antituberculosis therapy in...

to investigate the effect of salinity stress on membrane stability index, membrane lipid peroxidation, catalase activity and protein content of fenugreek (trigonellafoenum) an experiment with five levels of short-term salinity stress (0, 50, 100, 150 and 200 mm) was carried out at the laboratory of agriculture faculty of shahid bahonar university of kerman, iran. the treatments were arranged ba...

The presence of lipids in alveolar macrophages has been used clinically as an indicator of aspiration, a process associated with increased lung inflammation in animal models. The hypothesis is that the quantity of lipids in alveolar macrophages, measured as lipid-laden index (LLI), would correlate with lung inflammation in paediatric patients. Children with chronic respiratory symptoms (21 cyst...

OBJECTIVE Dyslipidemia with higher inflammatory states, disease activity, and longer disease duration in juvenile idiopathic arthritis (JIA) patients seemed to increase the risks of atherosclerosis. Tumor necrosis factor- α (TNF-α) receptor blocking agent etanercept has been proven to be effective in JIA. However, data about the correlation of anti-inflammatory treatment on lipid profiles and a...

The chain packing in ordered phases of lipid bilayers can be classified according to wide-angle X-ray diffraction (WAXS). For triclinic (T(‖)) and monoclinic (M(‖)) packing in crystalline L(c) phases, the wide-angle reflections index on an oblique lattice with spacings s(10)≠s(01)≠s(11), and each chain has four nearest neighbours. For orthorhombic (O(⊥)) packing in L(c) phases, and the rotation...