Cluster analysis refers to a class of data reduction methods used for sorting cases, observations, or variables of a given dataset into homogeneous groups that differ from each other. The present paper focuses on hierarchical agglomerative cluster analysis, a statistical technique where groups are sequentially created by systematically merging similar clusters together, as dictated by the dista...

BACKGROUND Hypertension is a complex biological trait that influenced by multiple factors. The encouraging results for hypertension research showed that the linkage analysis can be used to replicate other studies and discover new genetic risk factors. Previous studies linked human chromosome 14 to essential hypertension or blood pressure traits. With a Chinese population, we tried to replicate ...

The individualistic response of species to climate change is accepted by many although how this process works across several climate oscillations has not been widely considered. A cluster analysis using the Bray–Curtis metric with single linkage to show relative faunal similarity was performed on successively older British mammalian faunas to investigate whether they become progressively differ...

The expected value of the squared linkage disequilibrium is derived for a neutral locus associated with a chromosomal arrangement that is maintained in the population by strong balancing selection. For a given value of recombination, the expected squared linkage disequilibrium is shown to decrease as the intensity of selection maintaining the arrangement increases. The transient behavior of the...

This paper presents an extension of the finite polygenic mixed model of Fernando et al. (1994) to linkage analysis. The finite polygenic mixed model, extended for linkage analysis, leads to a likelihood that can be calculated using efficient algorithms developed for oligogenic models. For comparison, linkage analysis of 5 simulated 4021-member pedigrees was performed using the usual mixed model...

In the election of a hierarchical clustering method, theoretic properties may give some insight to determine which method is the most suitable to treat a clustering problem. Herein, we study some basic properties of two hierarchical clustering methods: α-unchaining single linkage or SL(α) and a modified version of this one, SL∗(α). We compare the results with the properties satisfied by the cla...

Community welfare is one of the important points for a region and also essence national development. The people in Indonesia fairly unequal, especially East Java. To be able to map an area its Java, way that can used use clustering. hierarchical clustering method methods grouping data. In clustering, single linkage, complete average linkage are suitable data, which will compare best use. result...

In a previous study, QTL for carcass composition and meat quality were identified in a commercial finisher cross. The main objective of the current study was to confirm and fine map the QTL on SSC4 and SSC11 by genotyping an increased number of individuals and markers and to analyze the data using a combined linkage and linkage disequilibrium analysis method. A modified version of the method ex...