نتایج جستجو برای: limited systemic scleroderma
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Background: A debate still exists concerning the role of occupational and environmental factors in pathogenesis systemic scleroderma (SSc). Objectives: Our aim was to explore associations between SSc utilizing an automatic semantic interpretation PubMed results. Methods: The literature search string: (“systemic sclerosis” OR “scleroderma”) AND (“occupational exposure” “environmental” “risk fact...
3 Tan E M, Rodnan G P, Garcia I, Moroi Y, FritzlerM J, Peebles C. Diversity of antinuclear antibodies in progressive systemic sclerosis. Arthritis Rheum 1980; 23: 617-25. 4 Giordano M. Classification of progressive systemnic sclerosis. International Conference on PSS (scleroderma). Austin, 20-23 October 1981. Arthritis Rheum in press. 5 Giordano M, Valentini G, Ara M, Tirri G, Capeili L, Vatti ...
Methods Single-blind clinical trial. The tissue samples obtained from patients PAS, hematoxylin and eosin, E-Cadherin, CTGF, Tunnel, and staining for TGF-b1 is applied and evaluated by light microscopy. Additionally, we have analyzed both TGFB1 level and mRNA expression analysis in plasma and tissue samples from patients. A total of 15 patients were enrolled in the study. These patients, who we...
BACKGROUND Pulmonary endothelium plays an important role in the mechanism of pulmonary arterial hypertension (PAH). However, there is only a few data regarding the systemic endothelium in this syndrome. This study focused on the systemic endothelial involvement in PAH. METHODS Endothelial function was evaluated in 54 patients with idiopathic (n=28), scleroderma-associated (n=10), chronic thro...
Raynaud’s phenomenon (RP) is one of the early clinical manifestations of diffuse connective tissue diseases (DCTD), such as systemic sclerosis (SSc), mixed connective tissue disease (MCTD), systemic lupus erythematosus (SLE), and dermatomyositis (DM)/ polymyositis (PM), and nailfold capillaroscopy (NC) enables an in vivo assessment of the morphology of cutaneous capillaries, and has been used f...
BACKGROUND Systemic sclerosis, or scleroderma, is a chronic and rare connective tissue disease with negative physical and psychological implications. Sources of emotional distress and the impact they have on the lives of people with scleroderma are not well understood. OBJECTIVES To gain an in-depth understanding of the emotional experiences and sources of emotional distress for women and men...
BACKGROUND The scleroderma is a complex autoimmune collagen disorder that can affect many organs simultaneously, as it occurs in the systemic sclerosis (SS), or only the skin, as it occurs in the localized scleroderma (LS). The neurological presentation is extremely uncommon, and even more uncommon are the symptoms of the scleroderma in the cerebellum. CASE DESCRIPTION We report the case of a...
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