Aggressive treatment of ischemia of the lower extremities has decreased the number of amputations in both diabetic and nondiabetic patients; combined vascular reconstruction and microvascular free-flap transfer has been used to improve distal perfusion and cover large tissue defects caused by the critical limb ischemia during the past 30 years. We present our experience with a 71-year-old diabe...

Foot ulcerations complicated by infection are the major cause of limb loss in people with diabetes. This is especially true in those patients with severe sepsis. Determining whether to amputate or attempt to salvage a limb often requires in depth evaluation of each individual patient's physical, mental, and socioeconomic status. The current report presents and juxtaposes two similar patients, a...

To determine whether long-term oral anticoagulant treatment was effective in improving graft performance and preventing major amputation following vein bypass surgery for femoropopliteal atherosclerosis, a clinical trial was conducted in one single center and continued during 10 years. After 130 patients had electively received a femoropopliteal vein graft, they were randomly assigned to a ther...

Acute limb ischaemia is both a limb-threatening and life-threatening surgical emergency. The clinical presentation of acute limb ischaemia can vary depending on the underlying aetiology as well as pathophysiology. While traumatic acute limb ischaemia becomes obvious in a trauma victim, nontraumatic ischaemia can be easily mistaken for other neurological or medical conditions. The rapidity with ...

ObjectiveThe aim of this study was to provide long term survival and limb salvage rates for patients with non-revascularisable (NR) chronic threatening ischaemia (CLTI).MethodsThis a retrospective review prospectively collected data, derived from randomised controlled trial (JUVENTAS) investigating the use regenerative cell therapy. Survival index in CLTI without viable options revascularisatio...

Management of major limb injuries is a daunting challenge, especially as many of these patients have severe associated injuries. In trying to save life, often the limb is sacrificed. The existing guidelines on managing such trauma are often confusing. There is scope to lay down such protocols along with the need for urgent transfer of such patients to a multispecialty center equipped to salvage...