Symptomatic improvement of patients with functional dyspepsia after drug therapy is often incomplete and obtained in not more than 60% of patients. This is likely because functional dyspepsia is a heterogeneous disease. Although great advance has been achieved with the consensus definitions of the Rome I and II criteria, there are still some aspects about the definition of functional dyspepsia ...

introduction: functional dyspepsia and digestive disorders are common, debilitating and costly. little information is available about the role of stress management in terms of cognitivebehavioral treatment of dyspepsia. the purpose of this study was to investigate the effectiveness of cognitive-behavioral stress management on functional dyspepsia symptoms in patients who referred to digestion c...

background :the cag pathogenicity island includes a number of genes, including cytotoxin-associated protein a (caga) and vacuolatingcytotoxin (vaca) genotypes, which are associated with bacterial virulence. although the role of caga and vaca in the virulence of helicobacter pylori (h. pylori) is well-established in epidemiological studies, the relationship between the caga and vaca genotypes in...

Impaired gastric accommodation is one of the most important etiologic factors in the pathophysiology of functional dyspepsia. Ultrasound is a potential alternative method to study changes in gastric volume as a reflection of gastric accommodation. Ultrasound is suitable for patients because it is a non-invasive, easily repeated and non-radioactive procedure, and a previous study has demonstrate...

BACKGROUND - Previous evidence trying to assess the risk of celiac disease among dyspeptic patients has been inconclusive, showing in some cases notorious discrepancies. OBJECTIVE - To determine the prevalence of celiac disease in patients with dyspepsia compared to healthy controls without dyspepsia. METHODS - Adult patients under evaluation for dyspepsia were invited to participate. Thes...

Dyspepsia is a common problem where many sufferers do not seek healthcare. The clinical impact of the condition in the community and the economic costs were assessed using data from a large cross sectional survey. Dyspepsia may be costing society 1 billion pounds each year in the UK. Thus dyspepsia is a huge clinical and economic burden and cost effective management strategies and treatments ar...

disorders and the potential role of eosinophils. Gastroenterol Clin North Am 2008;37:383–95. 25. Park MI, Camilleri M. Is there a role of food allergy in irritable bowel syndrome and functional dyspepsia? A systematic review. Neurogastroenterol Motil 2006;18:595–607. 26. Zuo XL, Li YQ, Li WJ, et al. Alterations of food antigenspecific serum immunoglobulins G and E antibodies in patients with ir...

BACKGROUND Functional dyspepsia is defined as at least a 3-month history of dyspepsia without structural explanation for the symptoms, and it accounts for most cases of dyspepsia. We designed this study to investigate functional dyspepsia among a Chinese population in Taiwan. METHODS Data from the medical records of 1,143 adult patients who underwent transoral upper endoscopy for symptoms of ...

OBJECTIVE Nonsteroidal antiinflammatory drug (NSAID) use is a known risk factor for gastrointestinal (GI) perforations, ulcers, and bleeds, but there are limited data on its association with the very common symptom of dyspepsia. Using published and unpublished data sources, we sought to determine estimates of the risks of dyspepsia associated with NSAIDs. METHODS We searched computerized data...