Grid is an e-Science project assisting life scientists to build workflows that gather and co-ordinate data from distributed, autonomous, replicated and heterogeneous resources. The provenance logs of workflow executions are recorded as RDF graphs. The log of one workflow run is used to trace the history of its execution process; however, by aggregating provenance logs of workflow reruns, or run...

1 Institute for Bioengineering and Biosciences (IBB), Department of Bioengineering, Instituto Superior Técnico, Universidade de Lisboa, Avenida Rovisco Pais, 1049-001 Lisbon, Portugal 2Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisbon, Portugal 3Institute for Systems and Robotics, Instituto Superior Técnico, Universidade de Lisboa, Avenida Rovisco Pais, 1049-001 Lisbon, Portug...

The China-UK Systems Biology Workshop 2005 was held during June 20–21 in the National Science Park of Zhejiang University, Hangzhou, China. It was organized by the Institute of Bioinformatics, Zhejiang University, and was initiated by Prof. Dr. Jun Zhu (Zhejiang University) and Prof. Dr. John Findlay (University of Leeds, UK). The workshop was part of the program called UK-China Partners in Sci...

Although a vast amount of life sciences data is generated in the form of images, most scientists still store images on extremely diverse and often incompatible storage media, without any type of metadata structure, and thus with no standard facility with which to conduct searches or analyses. Here we present a solution to unlock the value of scientific images. The Global Image Database (GID) is...

On October, 20, 2005, The Federal Trade Commission’s (“FTC”) Chief Administrative Law Judge, Stephen J. McGuire (“ALJ”), issued an Initial Decision finding that Evanston Northwestern Healthcare Corporation’s (“Evanston”) acquisition of Highland Park Hospital (“Highland Park”) violated § 7 of the Clayton Act. The ALJ ordered Evanston to divest itself of Highland Park within 180 days of the ALJ O...

The enteric nematode parasite Ascaridia galli modulate the immune system, of the hosts and eventually leads to malnutrition in the chicks which eventually results in the decreased return of products derived from poultry. The accurate interpretation of avian plasma proteins and the dramatic changes in protein fraction are important events in several diseases and may help in procuring a diagnosis...

Atomic Force Microscopy (AFM) techniques are used with oneor two-dimensional arrays of piezoresistive probes for parallel imaging. We present a newly designed AFM platform to drive these passivated piezoresistive cantilever arrays in air and liquid environments. Large area imaging in liquid as well as qualitative and quantitative analysis of biological cells are demonstrated by the means of pie...

Scanning probe based patterning techniques have the unique ability to deposit biological material into specific architectures on substrates and read and analyze the patterns using an atomic force microscope. Such devices are able to make much smaller biomolecule patterns, on the order of nanometers, than conventional techniques such as microcontact printing and optical lithography. A reduction ...

Text mining is a powerful technology for quickly distilling key information from vast quantities of biomedical literature. However, to harness this power the researcher must be well versed in the availability, suitability, adaptability, interoperability and comparative accuracy of current text mining resources. In this survey, we give an overview of the text mining resources that exist in the l...

classes that group together proteins with similar amino-acid subsequences and similar biological properties. We instigated Kbdock (Kb for “knowledge-based”) to address the problem of PPI modelling and classification at the domain level. In fact, as in many other complex scientific domains, big data approaches in the life sciences can only become viable by explicitly considering and making use o...