The Life Events Checklist (LEC), a measure of exposure to potentially traumatic events, was developed at the National Center for Posttraumatic Stress Disorder (PTSD) concurrently with the Clinician Administered PTSD Scale (CAPS) to facilitate the diagnosis of PTSD. Although the CAPS is recognized as the gold standard in PTSD symptom assessment, the psychometric soundness of the LEC has never be...

We examine whether adolescents' probability judgments for significant life events are predictive and accurate. We find significant correlations with actual experiences, reported on successive waves of a national survey. Mean probability judgments approximated observed outcome rates, or were optimistic, except that adolescents greatly overestimated their probability of dying prematurely.

OBJECTIVE Stress may play a role in the pathogenesis of the metabolic syndrome. However, the scant evidence available is not population-based, restricting the external validity of the findings. Our aim was to test associations between stressful life events, their accumulation, and the metabolic syndrome in a large population-based cohort. We also tested associations between stress and the indiv...

Twin studies that examine the effect of specific environmental risk factors on psychiatric disorders assume that there are no differences in prevalences of these risk factors between twins and singletons. Violation of this assumption signifies that the results from twin studies might not generalize to singletons. Another assumption, not only underlying twin studies but also epidemiological rese...

Thirty-one elderly depressive patients (diagnosed as suffering from depressive episode or recurrent depressive disorder according to LCD-10 diagnostic criteria for research) attending psychiatry O.P.D. or geriatric clinic at the All India Institute of Medical Sciences, New Delhi (AIIMS) and thirty-one elderly nonpsychiatric patients, attending geriatric clinic at AIIMS were subjected to a semi ...

The study investigated the role of stressful life events and family pathology in manic illness-selecting 30 cases of mania from Psychiatric Centre Jaipur and 30 normal controls from paramedical staff of psychiatric hospital. Both manics and normals were matched in terms of age, sex, education, marital status etc. All the subjects were subjected to Paykel's life events questionnaire, and an inte...

The use of DNA probes to monitor minimal residual disease in childhood acute lymphoblastic leukaemia. A. The polymerase chain reaction: a new tool for the detection of minimal residual disease in hae-matological malignancies. Tournay 0, et al. Detection of minimal disease in hematopoietic malignancies of the B lineage by using third-complimentarity-determining region (CDR-III) specific probes. ...