Studies have been carried out previously to determine whether mesenchymal stem cells (MSC) influence the progression of pulmonary fibrosis. Here, we asked whether MSC (derived from mouse bone marrow and human umbilical cord blood) produce factors that mediate lung fibroblast (LF) growth and matrix production. MSC-conditioned media (CM) were found by ELISA to contain significant amounts of PDGF-...

and Applied Analysis 3 then lim k Uf Lf, ∀f ∈ C X . 3.2 Moreover, if X is a compact metric space, then the convergence is uniform. Proof. Let f ∈ C X . The case when Lf f is trivial. Indeed, in this case, since Lf ∈ V andU preserves the elements of V, we haveUf ULf Lf , and hence Uf Lf , k 1, 2, . . . . If Lf / f , for sufficiently small ε > 0, the inverse image of the open set −ε, ε under the ...

The spread of tuberculosis (TB) in Asian countries is mainly due to co-existence and close association humans with elephants other domestic livestock. Infected animals tend shed the organism preclinical period which risks transmission infection from vice versa. Since chronic lack specific clinical signs, diagnosis remains challenging. present study focuses on utilization lipoarabinomannan (LAM)...

Lactoferrin receptor (LfR) is expressed in most mammalian tissues including placental trophoblasts and is presumed to mediate the internalization of lactoferrin (Lf). However, the physiological significance of trophoblast LfR is not understood. Using a cytotrophoblast cell model (BeWo) we demonstrated that transfection with LfR siRNA significantly decreased apo- but not holo-Lf uptake compared ...

the aim of this study was to characterize the effect of typhoid fever on pharmacokinetic parameters of levofloxacin (lf) and compare the pharmacokinetic parameters of the said antibiotic in healthy human volunteers and patients with typhoid fever. total of 12 subjects were divided into two groups “a” (healthy volunteers) and “b” (typhoid patients). single oral dose of lf 500 mg was given and 5 ...

BACKGROUND Genetic factors that predict responses to diet may ultimately be used to individualize dietary recommendations. We used physiogenomics to explore associations among polymorphisms in candidate genes and changes in relative body fat (Delta%BF) to low fat and low carbohydrate diets. METHODS We assessed Delta%BF using dual energy X-ray absorptiometry (DXA) in 93 healthy adults who cons...

Review and classification of electric load forecasting (LF) techniques based on artificial neural networks (ANN) is presented. A basic ANNs architectures used in LF reviewed. A wide range of ANN oriented applications for forecasting are given in the literature. These are classified into five groups: (1) ANNs in short-term LF, (2) ANNs in mid-term LF, (3) ANNs in long-term LF, (4) Hybrid ANNs in...

Citation: Lindsay SJ, Xu Y, Lisgo SN, Harkin LF, Copp AJ, Gerrelli D, Clowry GJ, Talbot A, Keogh MJ, Coxhead J, Santibanez-Koref M and Chinnery PF (2016) HDBR Expression: A Unique Resource for Global and Individual Gene Expression Studies during Early Human Brain Development. Front. Neuroanat. 10:86. doi: 10.3389/fnana.2016.00086 HDBR Expression: A Unique Resource for Global and Individual Gene...

Isolated rat hepatocytes bind and internalize bovine lactoferrin (Lf) and its bound iron in a Ca2+-dependent manner. In this study, we determined if one or both halves of Lf (N- and C-lobes) were responsible for the interaction of Lf with hepatocytes. We isolated three tryptic fragments of bovine Lf. Cleavage at Arg284-Ser285 generated two fragments: N-terminal pp36 that contained 80% of Lf N-l...

INTRODUCTION Regional citrate anticoagulation (RCA) for continuous renal replacement therapy is widely used in intensive care units (ICUs). However, concern exists about the safety of citrate in patients with liver failure (LF). The aim of this study was to evaluate safety and efficacy of RCA in ICU patients with varying degrees of impaired liver function. METHODS In a multicenter, prospectiv...