objective(s): enterotoxigenic escherichia coli (etec) strains are one of the primary causes of diarrhea in newborn calves and in humans, pigs, and sheep. igy technology has been identified as a promising alternative to generating a mass amount of specific antibody for use in immunotherapy and immunodiagnostics. the purpose of this study was to produce specific antibody by egg yolk antibody (igy...

in 1974, the world health organization (who) established the expanded program on immunization (epi) to ensure that all children have access to routinely recommended vaccines. since then, global coverage with the four core vaccines (bacille calmette guérin vaccine [for protection against tuberculosis], diphtheria-tetanus-pertussis vaccine [dtp], polio vaccine, and measles vaccine) has increased ...

infectious bursal disease virus (ibdv) infects young chickens and causes serious lose to the poultry industry, worldwide. previous attempts using purified bacterially expressed ibdv vp2 failed to elicit a protective immune response to the virus. this study was designed to investigate if the initial expressed protein contained neutralizing epitopes but became nonfunctional during purification st...

Introduction: Recently the most accurate diagnostic method in the diagnosis of prosthesis infection is the combination of Tc-99m labeled leukocyte/bone marrow imaging. However the diagnostic efficiency of the test is influenced because of its low spatial resolution. Recently SPECT/CT imaging is implicated in this test with efficient additional diagnostic improvement. In the dep...

background: different studies have demonstrated that a small proportion of healthy individuals receiving the hepatitis b (hb) vaccine do not produce protective levels of anti-hb antibody, a phenomenon which could be linked to certain human leukocyte an-tigen (hla) class-ii alleles or haplotypes. objectives: the present study was under-taken to determine the frequency of hla class-ii alleles in ...

abstract background ulcerative colitis (uc) is characterized by recurrent episodes of inflammation limited to the mucosal layer of the colon. calprotectin is a zinc and calcium binding protein derived from neutrophils and monocytes. it is easily detectable in tissue samples, body fluids, and stools, which makes it a potentially valuable marker of inflammation. the aim of the current study is to...

BACKGROUND The aim of the study was to evaluate the effectiveness of home visiting programmes on the uptake of childhood immunization. METHODS A systematic review was carried out of the literature of controlled studies evaluating home visiting programmes involving at least one post-natal visit, which included tasks within the remit of British health visiting and reporting outcomes relevant to...

The development of therapeutic monoclonal antibodies through mouse immunization often originates drug candidates that are not cross-reactive to the mouse ortholog. In such cases, and particularly in oncology, drug efficacy studies are performed on human tumor xenografts or with "surrogate" anti-mouse ortholog antibodies if targeting tumor host cells. Safety assessment of drug candidate(s) is pe...