Once considered the culmination of metastatic disease and a marker of the terminal end of a patient’s experience with cancer, leptomeningeal disease (LMD), also known as neoplastic meningitis and carcinomatous meningitis, has become an increasingly frequent complication of cancers (Bomgaars, Chamberlain, Poplack, & Blaney, 2002). LMD may even occur when a patient is in systemic remission. As pa...