The involvement of lymph nodes in leprosy is said to have been recorded by Gadesden in the 15th century (8) , and has been included as a feature in all modern textbooks dealing with leprosy. Klingmtiller (14), Basombrio (2), Schujman and Vaccaro (24) and Furniss (1) have described the gross and microscopic appearances of the lymph nodes in leprosy. Leprologists are unanimous that the lymph node...

BACKGROUND This study aimed to evaluate the risk factors associated with developing leprosy among the contacts of newly-diagnosed leprosy patients. METHODOLOGY/PRINCIPAL FINDINGS A total of 6,158 contacts and 1,201 leprosy patients of the cohort who were diagnosed and treated at the Leprosy Laboratory of Fiocruz from 1987 to 2007 were included. The contact variables analyzed were sex; age; ed...

Early case detection is now seen as one of the most important tasks for leprosy programs. It can improve experience people who develop disease, early treatment prevents many complications that frequently occur in whose diagnosis delayed. also an factor efforts to prevent ongoing transmission, reduces spread close contacts. Perhaps more importantly, it provides a platform appropriate management ...

BACKGROUND Low temperatures and slow blood flow may result from peripheral neuropathy caused by leprosy, and the simple detection of cold fingers could already be a preliminary classification for these patients. OBJECTIVE To investigate whether infrared thermography would be able to measure this change in temperature in the hands of people with leprosy. METHOD The study assessed 17 leprosy ...

Background: Recent data regarding demography, clinical presentation and molecular diagnosis of leprosy patients are lacking in Bangladesh. Methods: A cross sectional study on 55 leprosy cases of 16–70 years old, both sexes was done. Ziehl-Neelsen (Z-N) stain, histopathology and PCR of skin specimens were done. Results: 40% patients were between 21–30 years, mean age 34·5 years, male to female r...

BACKGROUND With approximately 250,000 new leprosy cases detected annually, transmission of M. leprae appears to be ongoing in many areas of the world. By studying prospectively the number of leprosy patients found in a population sample at the beginning of the study (prevalence) and the number of new patients found during the 6-year observation period (incidence), we aim to understand better th...

Background Leprosy remains an important cause of preventable disabilities. After the advent of multidrug therapy, new leprosy cases have come down dramatically. Despite this achievement, India, which contributes 60% of the global leprosy burden, faces some challenges to eliminate the disease, including active transmission in the community and delayed diagnosis of leprosy patients. Objectives Th...

BACKGROUND although the foci of leprosy once present in Spain are now under control and almost inactive, isolated cases are still occasionally diagnosed. Meanwhile, population migration has brought about an increase in the incidence of cases corresponding to individuals from countries where leprosy is endemic, leading to changes in the epidemiology of this disease. OBJECTIVES the aim of this ...

Leprosy is not a disease of modern civilization and industrialization, but its origin is as old as 4600 BC. Although the cure of leprosy is possible by MDT, there are certain misbelieves in the mind of leprosy patients leads to delay in disease reporting. Wandering of the patient from one healer to another healer also one of the cause that delays the start of MDT. It is known fact that the dela...

BACKGROUND Leprosy is a chronic infectious disease primarily affecting the peripheral nervous system and skin. Multibacillary leprosy is associated with nerve damage which could contribute to myelin alteration. As ceramide is a constituent of myelin sheath, the present study aimed to compare anti-ceramide antibody titre in paucibacillary and multibacillary leprosy patients with controls. METH...