Abstract Background Until 2021, the strongest guidelines on surgical correction of severe aortic regurgitation (AR) focused left ventricular systolic function (LVEF) and presence symptoms. However, those situations lead to an outcome penalty, even after correction. Left ventricle end-systolic diameter (LVESD) gained in strength 2021 European guidelines. Moreover, more inclusive cut-off values a...

Symptoms of congestive heart failure frequently reflect abnormalities in both systolic and diastolic performance. While much work has been reported regarding the mechanisms by which positive inotropic and vasodilator therapy affect systolic performance, little is known about their effect on diastolic function. In 12 patients with diffuse congestive cardiomyopathy micromanometer left ventricular...

BACKGROUND There are no randomized, controlled trial data to support the benefit of beta-blockers in patients with asymptomatic left ventricular systolic dysfunction. We investigated whether beta-blocker therapy ameliorates left ventricular remodeling in asymptomatic patients with left ventricular systolic dysfunction. METHOD AND RESULTS Patients with left ventricular ejection fraction <40%, ...

A new Doppler-derived index of the rate of left ventricular (LV) pressure rise (AP/At) was evaluated for the prognostic stratification of patients with chronic mitral regurgitation. The index is derived from the continuous wave Doppler mitral regurgitation signal by dividing magnitude of LV-left atrial pressure gradient rise (Ap) between 1 and 3 m/sec of the mitral regurgitation velocity signal...

Background. Myocardial stretch and increased ventricular filling can lead to increased rates of myocardial protein synthesis. In animal studies, left ventricular mass increases after pericardiectomy, suggesting relief of a biologically meaningful restraining role and a resultant stimulus for growth. The present study was designed to test the hypothesis that combined thoracotomy and pericardioto...

BACKGROUND Myocardial stretch and increased ventricular filling can lead to increased rates of myocardial protein synthesis. In animal studies, left ventricular mass increases after pericardiectomy, suggesting relief of a biologically meaningful restraining role and a resultant stimulus for growth. The present study was designed to test the hypothesis that combined thoracotomy and pericardiotom...

Purpose: To evaluate the coronary thrombolytic effect of atorvastatin plus percutaneous intervention (PCI) for treatment acute myocardial infarction.Methods: From April 2019 to October 2020, 88 patients with infarction who were treated in Zhangqiu District People's Hospital randomly assigned receive either PCI (conventional group) or (combined group). Myocardial injury index, TnI, and creatine ...

OBJECTIVE To assess the value of cardiopulmonary exercise testing in predicting prognosis in a cohort of elderly patients with chronic heart failure (CHF). DESIGN A retrospective cohort study of all patients with CHF over the age of 70 years assessed between January 1992 and May 1997. SETTING Tertiary centre. PATIENTS 50 patients (mean (SD) age 75.9 (4.5) years, 8 women) with CHF New York...

To analyze cardiovascular dynamics in essential hypertension, 81 subjects with untreated mild essential hypertension (mean blood pressure, 112 +/- 14 mm Hg) and 87 normotensive subjects from the same working population were studied by echocardiography and simultaneous blood pressure determination. Hypertensive subjects had significantly higher pulse pressure, stroke volume index, cardiac index,...

In most patients with aortic regurgitation, valve replacement results in reduction in left ventricular dilatation and an increase in ejection fraction. To determine the relation between serial changes in ventricular dilatation and changes in ejection fraction, we studied 61 patients with chronic severe aortic regurgitation by echocardiography and radionuclide angiography before, 6-8 months afte...