Our experience with a patient who had an angioma of the anterior wall of the left ventricle that produced complete occlusion of the left main coronary artery is presented. Diagnosis was made before surgery from findings on cineangiographic studies. Successful surgical treatment consisted of a double aortocoronary bypass to the left anterior descending and obtuse marginal coronary arteries. The ...

The purpose of our study was to investigate whether loss of myocardial contraction immediately after coronary occlusion was nonuniform, and if pretreatment with carvedilol, a vasodilating nonselective beta-adrenoceptor antagonist, could retard loss of contraction after coronary artery occlusion. Feline hearts were subjected to acute regional ischemia by total occlusion of the left anterior desc...

Left ventricular anterior wall metabolism was investigated concurrently with global myocardial metabolism by simultaneous preoperation sampling of anterior interventricular venous (AIV) and coronary sinus (CS) as well as arterial bloods in seven patients with severe obstructive lesions of the major coronary arteries, including left anterior descending. Postoperative study was performed two week...

BACKGROUND Previous work showed a twofold increase in stiffness of nonischemic myocardium at the base during ischemia of the left anterior wall. Whether the diastolic response of nonischemic myocardium to remote ischemia depends on the localization of the ischemic or the nonischemic area is unknown. METHODS In dogs with open chests, regional function in ischemic and nonischemic myocardium was...

AIMS The accuracy of magnetic resonance angiography in detecting proximal coronary artery stenoses is unclear. We postulated that fast magnetic resonance angiography is capable of (1) imaging proximal coronary arteries, and (2) detecting stenoses of > or = 50% of their luminal diameter. METHODS AND RESULTS Thirty-five patients, referred for analysis of angina pectoris, underwent both conventi...