We elucidate the effects of incorporating surfactants into electrospun poly (ɛ-caprolactone) (PCL) scaffolds on network homogeneity, cellular adherence and osteogenic differentiation. Lecithin was added with a range of concentrations to PCL solutions, which were electrospun to yield functionalized scaffolds. Addition of lecithin yielded a dose-dependent reduction in scaffold hydrophobicity, whi...

Lecithin-cholesterol acyltransferase (LCAT) is a plasma enzyme which catalyzes the transacylation of the sn-2-fatty acid of lecithin to cholesterol, forming lysolecithin and cholesteryl ester. We have recently proposed a covalent catalytic mechanism for LCAT in which lecithin cleavage proceeds via the formation of a transition state tetrahedral adduct between the oxygen atom of the catalytic se...

There is in normal plasma an enzyme activity which converts labeled lysolecithin to lecithin by an energy-independent low density lipoprotein-activated pathway. Studies were undertaken to compare the identity of this enzyme with lecithin-cholesterol acyltransferase. During purification of the enzyme by ultracentrifugation and by chromatography on high density lipoprotein affinity column, DEAE-S...

Hanahan and Jayko (1952) isolated a pure individual unsaturated lecithin, L-ox-(dipalmitoleyI)lecithin, from fresh baker's yeast by adsorption on alumina. They showed that hydrogenation of this material produced the corresponding saturated lecithin which was identical with the synthetic L-oc-(dipalmitoyl)-lecithin of Baer and Maurukas (1952). The latter compound, when used in combination with c...

A simple method for the rigorous derivation of lithogenic index or percent cholesterol saturation, embodying both relative and total lipid concentrations, is described. We recently demonstrated that under physiological conditions only two key physical-chemical variables, the bile salt-lecithin ratio and the total lipid (bile salts + lecithin + cholesterol) concentration determine the equilibriu...

Bile colloids containing taurocholate and lecithin are essential for the solubilization of hydrophobic molecules including poorly water-soluble drugs such as Perphenazine. We detail impact Perphenazine concentrations on taurocholate/lecithin using analytical ultracentrifugation, dynamic light scattering, small-angle neutron nuclear magnetic resonance spectroscopy, coarse-grained molecular dynam...

this study was conducted to evaluate the effect of different lecithin sources and their levels on growth performance and resistance to anoxia stress of rainbow trout (oncorhynchus mykiss) alevin with initial weight of 120 ± 4.08 g for 40 days. soybean and egg lecithin at 2, 4 and 6 ? levels were added to the diets. seven treatments by three replications were used in this experiment. therefore, ...

in whipping cream industry the recent trend is to reduce cream fat content without any changes in physical and whipping properties. stabilizers are widely used to improve physical and whipping properties of whipping cream. in this research, the effect of lecithin (0.1, 0.2 and 0.3%), carrageen an (0.01, 0.02 and 0.03%) and wp900 (0.1, 0.2 and 0.3%) was investigated on firmness, overrun, drainag...