BACKGROUND Various medicinal plants have been studied using modern scientific approaches. These plants have a variety of properties and various biological components that can be used to treat various diseases. However, harmful effects of plants are common clinical occurrence. OBJECTIVE This study was designed to investigate toxicological assessment of acute and chronic methanol leaf extract o...

AIM The purpose of this study was to determine the postpartum estrus cycle of guinea pigs (Cavia cobaya) using Anredera cordifolia leaf extract. MATERIALS AND METHODS Materials used were 8 males and 8 females of C. cobaya with body weight ranged 400-450 g. Mating ratio applied was 1:1. Treatments given were 0, 10, 50 and 90 mg of A. cordifolia leaf extract/head, designated as T0, T1, T2 and T...

Pandemic infection or reemergence of Enterovirus 71 (EV71) and coxsackievirus A16 (CVA16) occurs in tropical and subtropical regions, being associated with hand-foot-and-mouth disease, herpangina, aseptic meningitis, brain stem encephalitis, pulmonary edema, and paralysis. However, effective therapeutic drugs against EV71 and CVA16 are rare. Kalanchoe gracilis (L.) DC is used for the treatment ...

The objective of the study was to investigate the antidiabetic action of aqueous extract of Cassia glauca leaf in different models of rats. The antidiabetic activity of aqueous extract of Cassia glauca leaf was evaluated by using normal and streptozotocin-induced diabetic rats. After the oral administration of aqueous extracts at doses of 500 mg/kg body weight, blood glucose levels and body wei...

The antibacterial activity of leaf juice and extracts of Moringa oleifera Lam., belonging to the family Moringaceae, was determined in vitro, using disc diffusion and minimum inhibitory concentration (MIC) determination method against human pathogenic bacteria. The fresh leaf juice (10 μl disc-1), powder from fresh leaf juice, cold water extract of fresh leaf, each of 1175 μg disc-1, displayed ...

Background: Considering the increasing resistance of bacteria to antibiotics and the presence of antibacterial agents in plantsObjectives: the aim of this study was the antimicrobial and antibiofilm activity of Tecomella undulata and Momordica charantia ethanol and aceton leaf extract on antibiotic resistance Acinetobacter baumannii.Methods: The leaves of Tecomella undulata and Momo...

Background: Considering the increasing resistance of bacteria to antibiotics and the presence of antibacterial agents in plantsObjectives: the aim of this study was the antimicrobial and antibiofilm activity of Tecomella undulata and Momordica charantia ethanol and aceton leaf extract on antibiotic resistance Acinetobacter baumannii.Methods: The leaves of Tecomella undulata and Momo...

The present study was carried out to screen and evaluate the antimicrobial activity of leaf extracts from Aegle marmelos (L.) Corr. Petroleum ether, Dichloromethane, Chloroform, Ethanol and Aqueous extract of the leaves were tested against selected Gram positive and Gram negative bacteria. Results depict that phytochemical extracts of A. marmelos exhibited significant anti-bacterial activity. H...

OBJECTIVE Vernonia amygdalina (V. amygdalina) leaf is locally employed in the Southern region of Nigeria in the treatment of malaria infection. This study evaluated the in vivo antiplasmodial, antioxidant and immunomodulatory effect of ethanol extract of V. amygdalina leaf. MATERIALS AND METHODS The active principles of the dried leaf were extracted with ethanol. For quality validation, chemi...

The polyphenolic constituents and antioxidant activity of aqueous and acetone extracts of Vachellia karroo leaves were determined in order to evaluate its efficacy in scavenging radicals such as DPPH, ferric reducing power and nitric oxide as an antioxidant model. The flavonols and flavonoid and phenolic content of the leaf extracts were also accessed using benchmark phytochemical reaction meth...