Bioengineering of small-diameter blood vessels offers a promising approach to reduce the morbidity associated with coronary artery and peripheral vascular disease. The aim of this study was to construct a two-layered small-diameter blood vessel using smooth muscle cells (SMCs) and endothelial cells (ECs) differentiated from human adipose-derived stem cells (hASCs). The outer layer was construct...

The present paper deals with a two-layered mathematical model for blood flow through stenotic tube in porous medium under the effect of an applied magnetic field. In this mathematical model, the blood is considered as Newtonian fluid of variable viscosity in the central region and plasma fluid which is considered as Newtonian fluid of constant viscosity in the peripheral region of the stenotic ...

Bacterial nanocellulose (BNC) has demonstrated a tempting prospect for applications in substitute of small blood vessels. However, present technology is inefficient in production and BNC tubes have a layered structure that may bring danger after implanting. Double oxygen-permeable silicone tubes in different diameters were therefore used as a tube-shape mold and also as oxygenated supports to c...

Centrioles are microtubule-based cylindrical structures that exhibit 9-fold symmetry and facilitate the organization of centrosomes, flagella, and cilia [1]. Abnormalities in centrosome structure and number occur in many cancers [1, 2]. Despite its importance, very little is known about centriole biogenesis. Recent studies in C. elegans have highlighted a group of molecules necessary for centri...

OBJECTIVE Our objective is to build a model that explains the association between the exposure to trace elements in the soil and the risk of neural tube defects. METHODS We built a function with different parameters to describe the effects of trace elements on neural tube defects. The association between neural tube defects and trace element levels was transformed into an optimization problem...

In the field of genetic research and the subsequent rise of biobanks an intensive discussion is taking place on national and international levels about property and personality rights to one’s own body and body parts. The authors attempt to develop on the basis of the current controversially discussed law a concept of property, which can solve the legal and bioethical problems of the multiple u...

Considering a kinematical velocity admissible field, the upper bound method has beenused for predicting the amount of pressure in hydroforming of sheet metals. The effects of workhardening, friction and blank size have been considered in pressure prediction. Also the effect ofsheet thickness variation has been considered in the present work formulations. The relation betweenpressure and punch s...