OBJECTIVE To determine whether levels of PH-20, a hyaluronidase similar to that found in human sperm, are elevated in laryngeal cancer tissue. DESIGN In this case-control study. reverse transcription polymerase chain reaction was used to measure levels of PH-20 messenger RNA in tissue taken from laryngectomy specimens. SETTING A university medical center. PATIENTS We compared tissue sampl...

Abstract Expressing syllable weight by moras leads to two problems. First, there are languages, such as Wolof, with long vowels and geminates, which both make a bimoraic, but where only vowels, not count heavy for stress. Second, languages in closed syllables light stress, segmental modifications (laryngeal metathesis Cayuga degemination Chugach Alutiiq). It is argued that two-layered mora mode...

Left recurrent laryngeal nerve palsy rarely results from cardiac disease. We present 2 cases of left recurrent laryngeal nerve palsy caused by thoracic saccular aortic aneurysms. One patient suffered an aortic aneurysm rupture one month after the advent of hoarseness, necessitating emergency surgery with aortic arch replacement. The other patient underwent elective aortic arch replacement surge...

A system for acoustic analysis of pathological voices is proposed. The vocalized part of the voice signal is separated and all glottal cycles are traced by means of a cross-correlation detector. Based on the so determined beginning and duration of all glottal cycles, shimmer, jitter, several harmonics-to-noise ratios and other widely used acoustic parameters are calculated. New parameters are a...

OBJECTIVE Persistent hoarseness due to recurrent laryngeal nerve paralysis (RLNP) reduces the quality of life unless it is adequately treated. This study examined the indications for phonosurgical intervention in patients with RLNP. MATERIALS AND METHODS The medical records of the Ehime University Hospital, Ehime, Japan, from October 1976 until December 1997 were reviewed retrospectively to i...

BACKGROUND The ProSeal is a wire-reinforced laryngeal mask airway with an additional drain tube that leads to the distal tip of the laryngeal cuff. The design should improve the seal with the larynx. METHODS The ProSeal and classic laryngeal mask airways were compared in 180 patients in a randomized crossover study. Patients were anaesthetized without neuromuscular blocking drugs. RESULTS T...

UNLABELLED Laryngeal microsurgery is a kind of treatment for various laryngeal diseases. Because of the need of long instruments and delicate maneuvers, involuntary movements represent relevant difficulty and may be responsible for unintended post-operative results. AIM This study proposes a new stabilization system, flexible and versatile, which can significantly reduce involuntary movements...