By capturing time-lapse images of primary stromal-vascular cells (SVCs) derived from rat mesenteric adipose tissue, we revealed temporal and spatial variations of lipid droplets (LDs) in individual SVCs during adipocyte differentiation. Numerous small LDs (a few micrometers in diameter) appeared in the perinuclear region at an early stage of differentiation; subsequently, several LDs grew to mo...

Time-lapse geophysical measurements and seismic imaging methods in particular are powerful techniques for monitoring changes in reservoir properties. Traditional time-lapse processing methods treat each dataset as an independent unit and estimate changes in reservoir state through differencing these separate inversions. We present a general least-squares approach to jointly inverting time-varyi...

Knowledge of changes in reservoir properties resulting from extracting hydrocarbons or injecting fluid is critical to future production planning. Full-waveform inversion (FWI) of time-lapse seismic data provides a quantitative approach to characterize the changes by taking the difference of the inverted baseline and monitor models. The baseline and monitor data sets can be inverted either indep...

Embryo evaluation and selection is fundamental in clinical IVF. Time-lapse follow-up of embryo development comprises undisturbed culture and the application of the visual information to support embryo evaluation. A meta-analysis of randomized controlled trials was carried out to study whether time-lapse monitoring with the prospective use of a morphokinetic algorithm for selection of embryos im...

BACKGROUND Embryo selection is a vital part of in vitro fertilization (IVF) programs, with morphology-based grading systems having been widely used for decades. Time-lapse imaging combined with embryo morph kinetics may proffer a non-invasive means for improving embryo selection. We report the first ongoing and chemical pregnancies using Time-lapse embryo scope to select best embryos for transf...

Aviation, military, police, and health care personnel have been particularly interested in the operational impact of sleep restriction and work schedules given the potential severe consequences of making fatigue-related errors. Most studies examining the impact of sleep loss or circadian manipulations have been conducted in controlled laboratory settings using small sample sizes. This study exa...

The role of the Taub time gauge in cosmology is linked to the use of the densitized lapse function instead of the lapse function in the variational principle approach to the Einstein equations. The spatial metric variational equations then become the Ricci evolution equations, which are then supplemented by the Einstein constraints which result from the variation with respect to the densitized ...

Research exploring psychological dysfunction as a predictor of smoking cessation success may be limited by nonoptimal predictor variables (i.e., categorical psychodiagnostic measures vs. continuous personality-based manifestations of dysfunction) and imprecise outcomes (i.e., summative point-prevalence abstinence vs. constituent cessation milestone measures). Accordingly, this study evaluated t...

Automated microscopy enables in vivo studies in developmental biology over long periods of time. Time-lapse recordings in three or more dimensions to study the dynamics of developmental processes can produce huge data sets that extend into the terabyte range. However, depending on the available computational resources and software design, downstream processing of very large image data sets can ...