PURPOSE Previous reports indicated that pregnancy and corneal injury (CI) trigger alterations of lacrimal gland (LG) growth factor expression and redistributions of lymphocytes from periductal foci to acini. The purpose of this study was to test our hypothesis that pregnancy would exacerbate the changes induced by CI. METHODS Corneas were injured with scalpel blades, and, 2 weeks later, LGs w...

The lacrimal and third eyelid superficial glands produce the aqueous component of the preocular tear film. In this research, morphologic and morphometric assessments of the parenchyma and stroma of both lacrimal glands of healthy adult mongrel dogs were performed. Both lacrimal and third eyelid glands of fourteen dogs were collected, summing fiftysix samples. The macroscopic and morphometric da...

Institutional review board approval of the LV Prasad Eye Institute was obtained. Intrasaccal lacrimal sac granulomas are uncommon and are usually seen secondary to chronic inflammation. A 55-year-old woman presented with leftsided epiphora associated with discharge of 5 years. Irrigation and probing were suggestive of a nasolacrimal duct obstruction, and the patient underwent a powered endoscop...

Purpose The objective of this study was to ascertain the lacrimal drainage anomalies in a cohort of patients suffering from congenital rubella syndrome (CRS). Methods This was a retrospective case series performed in patients with CRS presenting with associated lacrimal drainage anomalies (LDA) over 6 years from 2011 to 2016. All the patients were confirmed as having CRS after clinical and la...

As part of an assessment for preeclampsia, a prenatal sonogram performed on a pregnant woman at 33 weeks 4 days' gestation showed ectrodactyly in all 4 fetal extremities. The woman's husband had a history of hand abnormalities but was unaware that his condition was genetic. His examination was notable for ectrodactyly, small, peg-shaped teeth, microretrognathia, nail dysplasia, and a history of...

IMPORTANCE Approximately 5% to 10% of patients continue to experience persistent epiphora following an anatomically successful dacryocystorhinostomy (DCR) for nasolacrimal duct obstruction or stenosis. OBJECTIVE To investigate the management and success rate of so-called "functional failure" of DCR for nasolacrimal duct obstruction by experienced lacrimal surgeons. DESIGN, SETTING, AND PART...

BACKGROUND The aims of the study are to assess the prevalence of bacteremia during dacryocystorhinostomy (DCR) and to assess whether there is a need for post-operative prophylaxis. Prospective interventional study of 52 consecutive dacryocystorhinostomy performed in 50 patients over a period of 1 year from 2013 to 2014. Blood was drawn under strict aseptic conditions during two separate time po...

PURPOSE To describe the clinical features and management of a patient with an extralacrimal dacryolith. METHODS Case report. RESULTS A 43-year-old woman remarked at a routine eye examination that a small, firm mass located for several years on the right side of her nose had recently become slightly larger. The mass had remained firm and nontender during this enlargement. She explicitly deni...

The role of silicone intubation in routine dacryocystorhinostomy (DCR) surgery remains unclear. Recent studies provide a higher level of evidence against intubation in DCR. Intubation of the nasolacrimal duct with silicone tubes has largely arisen as a result of history, anecdote and the evolution of DCR surgery rather than being based upon sound evidence. Silicone intubation has gained popular...