نتایج جستجو برای: labile toxins
تعداد نتایج: 28306 فیلتر نتایج به سال:
Concerns with rising atmospheric levels of CO2 have stimulated interest in C ̄ow in terrestrial ecosystems and the potential for increased soil C sequestration. Our objectives were to assess land management effects on soil organic carbon (SOC) dynamics and SOC sequestration for long-term studies in the tallgrass prairie region of the US. Major losses of SOC following conversion of native prairi...
One of the main problems in many diseases is pain which has soc ial, psychological and physical symptoms on patients. Due to the side effects of analgesic drugs, new effective compounds to reduce pain are needed. Ionic channels, acetylcholine and gamma aminobutyric acid receptors and molecules such as nitric oxide are involved in pain paths. Animal venoms contain small molecules with various p...
The genes for a new enterotoxin were cloned from Escherichia coli SA53. The new toxin was heat labile and activated adenylate cyclase but was not neutralized by antisera against cholera toxin or E. coli heat-labile enterotoxin. Subcloning and minicell experiments indicated that the toxin is composed of two polypeptide subunits that are encoded by two genes. The two toxin subunits exhibited mobi...
Standard dialyzer membranes, designed for diffusive clearance, do not effectively clear protein-bound uremic toxins, such as indoxyl sulfate (IS). To increase toxins removal, absorbents require a high specific surface area to achieve effective size-coupling removal of target toxins. However, the toxicity molecule is necessarily determined by size alone. As proof concept, we report on an electro...
Labile iron in hemosiderotic plasma and tissue are sources of iron toxicity. We compared the iron chelators deferoxamine, deferiprone and deferasirox as scavengers of labile iron in plasma and cardiomyocytes at therapeutic concentrations. This comprised: chelation of labile plasma iron (LPI) in samples from thalassemia patients; extraction of total cellular iron; accessing labile iron accumulat...
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