Tessari, Paolo, Edward Kiwanuka, Anna Coracina, Michela Zaramella, Monica Vettore, Anna Valerio, and Giacomo Garibotto. Insulin in methionine and homocysteine kinetics in healthy humans: plasma vs. intracellular models. Am J Physiol Endocrinol Metab 288: E1270–E1276, 2005. First published January 11, 2005; doi:10.1152/ajpendo.00383.2004.—Methionine is a sulfur-containing amino acid that is reve...

An enzymic activity which catalyzes the reduction of N-acetyl-methionine sulfoxide to l-N-acetyl-methionine has been observed in a wide variety of plant tissues. Its activity depended on the presence of dithiotreithol in the incubation medium. l-Methionine-sulfoxide was essentially inactive as a substrate. Of all the physiological reductants tested, only thioredoxin partially replaced dithiothr...

In earlier papers (l-3) we have reported that the accumulation of adenine thiomethylriboside (5’-thiomethyladenosine) in yeast depends upon the presence of methionine in the culture medium. The mechanism of the reaction has now been studied and some of the results will be reported here. Attempts were made to determine the size of the fragment contributed by methionine toward formation of the nu...

We have obtained deuterium (2H) nuclear magnetic resonance (NMR) spectra and spin-lattice relaxation times (T1) of L-[epsilon-2H3]methionine, L-[epsilon-2H3]methionine in a D,L lattice, and [S-methyl-2H3]methionine in the crystalline solid state, as a function of temperature, in addition to obtaining 2H T1 and line-width results as a function of temperature on [epsilon-2H3]methionine-labeled sp...

Gentamicin C complex, produced by Micromonospora purpurea1*2), is composed of three components, Cla, C2 and Q (Fig. 1). These components are methylaminoglycosides, which are distinct from other related antibiotics such as the kanamycins, neomycinsand paromomycins. As seen in Fig. 1, gentamicins Cla, C2, and Q possess one C-methyl and one N-methyl group, two C-methyl and one N-methyl groups and ...

“Sand 3H-labeled short, nascent peptides have been extracted from mouse myeloma ribosomes after incubation of myeloma fragments with [?S]methionine and r3H]amino acids. Edman analysis of these peptides reveals that most of the methionine is present at the N terminus but that other N-terminal amino acids are also present. Light chains synthesized by the RPC-20 tumor fragments were purified from ...