Objectives To evaluate the impact of total knee replacement on quality of life in people with knee osteoarthritis and to estimate associated differences in lifetime costs and quality adjusted life years (QALYs) according to use by level of symptoms.Design Marginal structural modeling and cost effectiveness analysis based on lifetime predictions for total knee replacement and death from populati...

BACKGROUND Studies on exercise in knee osteoarthritis (OA) have focused on elderly subjects. Subjects in this study were middle-aged with symptomatic and definite radiographic knee osteoarthritis. The aim was to test the effects of a short-term, high-intensity exercise program on self-reported pain, function and quality of life. METHODS Patients aged 36-65, with OA grade III (Kellgren & Lawre...

INTRODUCTION Arthroscopic surgery is a very common orthopaedic procedure. While several trials have investigated the effect of knee arthroscopy for middle-aged and older patients with meniscal tears, there is a paucity of trials comparing meniscal surgery with non-surgical treatment for younger adults. The aim of this randomised controlled trial (RCT) is to investigate if early arthroscopic sur...

background and aims: osteoarthritis is one of the most common arthritis in elderly. we evaluated to compare the effect of topical application of eugenia caryophylata extract and topical diclofenac in primary knee osteoarthritis.methods: this randomized double-blind clinical trial study was carried out upon 105 patients with primary knee osteoarthritis. patients were selected randomly and divide...

background: this is a case series of 76 knees of 62 patients who underwent upper tibial valgus osteotomy for treatment of medial compartment osteoarthritis during a 20-year period and who were followed for a mean of 7.6 years.   methods: the patients were evaluated by validated outcome assessment systems of general health status short form (sf-36), the western ontario mcmaster osteoarthritis in...

BACKGROUND The purpose of this study was to examine the relationship between self-reported falls, doctor-diagnosed knee osteoarthritis (OA), and health-related quality of life (HRQoL). We hypothesized that falls and knee OA would be associated with poor HRQoL on both disease-specific and generic measures. METHODS This cross-sectional study used data from the publicly available Osteoarthritis ...

PURPOSE To compare the outcome following total knee arthroplasty (TKA) in obese and non-obese Asian patients. METHODS 27 obese patients were compared with 27 non-obese controls matched for age, gender, diagnosis (osteoarthritis), prosthesis, preoperative Knee Society knee and function scores, preoperative Oxford Knee Score, and follow-up duration. All TKAs were performed by a single surgeon. ...

Objective: The purpose of this article is to describe and recommend patient-reported outcome instruments for use in patients with articular cartilage lesions undergoing cartilage repair interventions. Methods: Nonsystematic literature search identifying measures addressing pain and function evaluated for validity and psychometric properties in patients with articular cartilage lesions. Results:...