In this paper we consider a kit planning problem where demand occurrences are not for individual items, but for kits (a group of items). Each kit contains an arbitrary number of items. Kit demands occur according to a Poisson process. Whenever a kit demand occurs, only one item from the kit is used and the rest is returned as unused. The item that will be used from the kit is not known in advan...

The receptor tyrosine kinase c-Kit plays a critical role in hematopoiesis, and gain-of-function mutations of the receptor are frequently seen in several malignancies, including acute myeloid leukemia, gastrointestinal stromal tumors, and testicular carcinoma. The most common mutation of c-Kit in these disorders is a substitution of the aspartic acid residue in position 816 to a valine (D816V), ...

Previously an increased frequency of KIT aberrations in mucosal melanomas was reported, whereas c-KIT in most types of cutaneous melanomas does not appear to be of pathogenetic importance. Imatinib has become the standard of care in other cancers with KIT mutations such as gastrointestinal stromal tumors. Recently 12 cases of metastatic melanoma and KIT-activating mutations have been published ...

This paper presents a novel kit application of a Bluetooth technology so-called ‘Fever Watcher-kit’ (FW-kit). FW-kit facilitates monitoring and tracking the children’s temperature in a safe way as needed. The FW-kit consists of two parts: temperature device and mobile application. The temperature device measures the temperature at the surface of the children’s skin and broadcasts the measured t...

Background: Recent studies have shown that KIT is expressed in the cytoplasm of the spermatogonia, acrosomal granules and leydig cells. Reduction in KIT expression in oligozoospermia with an increase in the germ cell apoptosis process. Three single-nucleotide polymorphisms (SNPs) have been identified and these have been studied to discover KIT role in the male infertility. The aim of this study...

Protein kinase signal-transduction pathways play critical roles in regulating nociception. The c-kit receptor contributes to pain regulation in the spinal cord and is present on both peripheral and central terminals. Expression of c-kit was demonstrated in human trigeminal and spinal ganglia. However, the brainstem expression of c-kit was overlooked. We aimed to evaluate it by immunohistochemis...