Flux balance analysis (FBA) is a linear programming-based framework widely used to predict the behavior, in terms of the resulting flux distribution, of cellular organisms in different media. FBA models are constructed using only stoichiometric information, and for this reason they sometimes fail in predicting fluxes precisely. In this work, we formally define the concept of hybrid FBA/kinetic ...

In this paper, a method is proposed for geometrically constructing thick panel structures that follow the kinetic behavior of rigid origami by using tapered or two-ply panels and hinges located at their edges. The proposed method can convert generalized pattern of rigid-foldable origami into thick panels structure with kinetic motion, which leads to novel designs of origami for various engineer...

We propose a new kinetic model for surface segregation during vapor phase growth that takes into account multiple mechanisms for segregation, including mechanisms for inter-layer exchange and surface diffusion. The resulting behavior of the segregation length shows temperature and velocity dependence, both of which have been observed in experiments. We compare our analytic model to experimental...

Background: PutA from Escherichia coli is a bifunctional enzyme and transcriptional repressor in proline catabolism. Results: Steady-state and transient kinetic data revealed a mechanism in which the two enzymatic reactions are coupled by an activation step. Conclusion: Substrate channeling in PutA exhibits hysteretic behavior. Significance: This is the first kinetic model of bi-enzyme activity...

The initial rate of formation of chlorine dioxide in the chlorite-tetrathionate reaction changes in an unusual fashion. The formal kinetic order of both reactants varies over a very wide range. Moreover, chlorite ion behaves not just as a simple reactant, but also as a self-inhibitor. A five-step scheme, derived from an eight-step mechanism, is proposed in which the autocatalytic formation of H...

background: the purpose of this study was to investigate the ratio of electromyography (em g) activities of the vastus medialis obliqus (vmo) and vastus lateralis (vl) within seven angles of knee joint range of motion using isometric contraction in open kinetic chain (ok c) and closed kinetic chain (ckc). methods: the dominant knees of 44 healthy female subjects (mean age: 24.84 with range: 20-...

We present a solvable kinetic lattice model which includes microscopic disorder, namely, random exchange energies ~between pairs of spins! fluctuating randomly with time. This, which may ideally model fast ionic diffusion in magnetic systems, impedes reaching equilibrium, in general. The resulting nonequilibrium steady states exhibit additional randomness which induces complex behavior, includi...

Differences in the kinetic behavior of aldol reactions compared to aminoxylation and amination reactions are rationalized by consideration of the ratedetermining step in each case. Both autoinductive behavior and the rate-enhancing effect of additives are attributed to an effect on the enamine formation step.