Objective: The present study was designed to investigate the protective effects of hydroalcoholic extract of Rheum turkestanicum against HgCl2 hepatorenal toxicity in rats. Materials and Methods: Animals were randomly divided into five groups (n= 6 in each group) and received HgCl2 and plant’s extract, intraperitoneally. Group1 received saline (1 mL/kg/day), group 2 received extract (200 mg/kg/...

Kidney disease is worldwide the 12th leading cause of death affecting 8-16% of the entire population. Kidney disease encompasses acute (short-lasting episode) and chronic (developing over years) pathologies both leading to renal failure. Since specific treatments for acute or chronic kidney disease are limited, more than 2 million people a year require dialysis or kidney transplantation. Severa...

background: diagnosis of kidney scar could prevent vesico urethral reflax and its complications such as hypertension and renal failure. this study was conducted to determine average kidney length and volume in infants by sonography to accurate diagnosis of scars. methods: this study was conducted on infants with the history of uti who referred to imam reza hospital, kermanshah iran, for dmsa sc...

The purpose of the study was to determine effect maternal glucocorticoids on experimental growth retardedrats and undernutrition in different gestation periods for function kidney. This studyhad two sections. In first section, 5 groups were formed. 10g/d diet given 1st, 2nd, 3rd trimesterand throughout pregnancy period. control group fed a normal diet. second 3 groupsformed all rats take 10 g/d...

The current review is informed about the effectiveness of plant-derived functional components that aids in regulation and health endocrine glands. glands include thyroid, adrenal, hypothalamus, pituitary pineal, ovaries testes play vital functions our body such as growth development, metabolism, mood reproduction controlled by hormones. abnormalities are formed various disorders, some major dis...

To understand renal functions and disease, it is important to define the molecular constituents of the various compartments of the kidney. Here, we used comparative transcriptomic analysis of all major organs and tissues in the human body, in combination with kidney tissue micro array based immunohistochemistry, to generate a comprehensive description of the kidney-specific transcriptome and pr...

background: diabetes mellitus is an alarming life style disease in the modern world. exploitation of the anti-diabetic drugs for the amelioration of diabetes and associated life style diseases has become an imperative concern. in this milieu, this study was designed to explore the plausible effects of metformin intervention on hepatic and renal functions in a rat model of alcoholic liver diseas...

To demonstrate the expression of heat shock proteins (Hsps) in the kidney, 5 kinds of Hsps, namely, Hsp70, Hsp72, Hsp86, Hsp90, and Hsp27, were examined in pigs after 6-h-transports by using western blot analysis. All 5 Hsps were detected in the kidneys of both the transported and control pigs. Hsp expression in the control pigs indicated that Hsps have some physiological functions in addition ...

Calcium (Ca(2+)) and phosphate (PO(4)(3-)) homeostasis are coordinated by systemic and local factors that regulate intestinal absorption, influx and efflux from bone, and kidney excretion and reabsorption of these ions through a complex hormonal network. Traditionally, the parathyroid hormone (PTH)/vitamin D axis provided the conceptual framework to understand mineral metabolism. PTH secreted b...