BACKGROUND Percutaneous renal biopsy (PRB) is essential for the diagnosis, prognosis, and management of children with unknown kidney disease. In this study, the safety and efficacy of PRB is investigated, and also the common etiologies of childhood kidney disease, based on histological findings. In addition, we explored the role of PRBs in the diagnosis of children who presented with persistent...

Antibody-mediated rejection is the leading cause of kidney graft dysfunction. The process diagnosing it requires performance an invasive biopsy and subsequent histological examination. Early sensitive biomarkers damage alloimmunity are needed to identify injury eventually limit need for a biopsy. Moreover, other scenarios such as delayed function or interstitial fibrosis tubular atrophy face sa...

BACKGROUND BK virus reactivation is a significant complication following renal transplantation that can result in graft failure. Reduction of immunosuppression and substitution of leflunomide for mycophenolate mofetil (MMF) has been used to treat this entity. OBJECTIVES To evaluate the use of leflunomide in BK viremia (BKV) and biopsy proven BK nephropathy (BKN) in kidney and kidney-pancreas ...

AIMS To determine the spectrum of renal lesions in patients with kidney involvement in non-Hodgkin's lymphoma (NHL) by renal biopsy. METHODS The clinical features and histological findings at the time of the renal biopsy were assessed for each patient. RESULTS We identified 20 patients with NHL and renal involvement, and the diagnosis of NHL was established following the kidney biopsy in 18...

Abstract Background and Aims Kidney biopsy may improve diagnostic accuracy aid in the management of cancer patients with kidney diseases. However, literature on utility survivors is lacking. We aimed to evaluate clinical characteristics who underwent biopsy, as well histological spectrum proven diseases this cohort. Method This was a single-center retrospective study all had native biopsies at ...

INTRODUCTION Bleeding is one of the most feared risks from a renal biopsy. To determine this risk, a clotting screen is performed prior to the biopsy to identify any coagulation abnormalities. In addition, concerns exist with respect to bleeding from platelet dysfunction and the special cases of paraprotenemia. METHOD Literature search of all the relevant articles in relation to bleeding risk...

Rationale & ObjectiveLimited data exist on patient perspectives of the implications kidney biopsies. We explored patients' alongside those clinicians to better understand how biopsies affect viewpoints and clinical utility biopsies.Study DesignProspective Cohort Study.Setting ParticipantsPatient participants in Kidney Precision Medicine Project, a prospective cohort study patients who undergo r...

Isolated endarteritis of kidney transplants is increasingly recognized. Notably, microarray studies revealed absence of immunologic signatures of rejection in most isolated endarteritis biopsy samples. We investigated if isolated endarteritis responds to rejection treatment and affects kidney transplant survival. We retrospectively enrolled recipients of kidney transplant who underwent biopsies...

Background and Aims: Primary glomerulonephritis (GN) is the major cause for end-stage renal disease (ESRD) considered to contribute in 52% cases. Kidney biopsy an essential tool nephrologists' clinical practice determining diagnosis, prognosis, therapy of a variety glomerular conditions. The purpose present study was determine primary diseases histopathological pattern among adult patients. Pat...

BACKGROUND/AIMS To improve procedural skill competence in real-time ultrasound-guided renal biopsy, we have developed an inexpensive simulation tool (a porcine kidney inserted under a turkey breast) that mimics biopsy conditions in human patients in terms of kidney size, depth, echogenicity and overall structural characteristics. This study investigated the utility of this simulation tool for i...