Objective(s): In this study, we investigated the protective effects of piperine on lead acetate-induced renal damage in rat kidney tissue. Materials and Methods: Forty male rats were divided into 5 groups: negative control (rats were given aquadest daily), positive control (rats were given lead acetate 30 mg/kg BW orally once a day for 60 days), and the treatment group (rats were given piperine...

Background: Cadmium is one of the most toxic heavy metals in our environment having a very strong ability to accumulate in body organs, especially in kidney. The present study was done to determine the genotoxicity and cytotoxicity in kidneys of rats exposed to cadmium. Methods: Male rats (n=30), kept in standard conditions were used in this study. The animals were randomly divided into 2 group...

The angiotensin I-converting enzyme (ACE) converts the inactive angiotensin I molecule to the active angiotensin II. ACE is rich in epithelium, endothelium, and neuroepithelial cells and it found largely on the brush border of intestine and kidney proximal tubules. ACE also presents in the serum. Some pulmonary and renal toxic drugs change the serum and tissue ACE contents. In this research ACE...

in order to study the role of the kidney in fish osmoregulation, freshwater acclimatized juvenile spottedscat (scatophagus argus l.) were subjected to four different salinities and observed for histomorphometricchanges of the kidney at 1, 2, 10 and 15 days post transfer time points. the overall morphological changesdisplayed by fish kidney included significant decrease in the density of collect...

introduction: renal dynamic study is a well-established and popular test in routine practice of nuclear medicine. the test is non-invasive, rapid and unique in evaluation of the kidney function. in despite of its clinical values, the parameters derived from renogram are physiologically meaningless. that is due to the fact that renogram is not the true kidney function. from mathematical points o...

congenital hepatic fibrosis (chf) is a rare disease that affects both the liver and kidneys.  congenital hepatic fibrosis (chf) is an autosomal recessive inherited malformation defined pathologically by a variable degree of periportal fibrosis and irregularly shaped proliferating bile ducts. affected individuals also have impaired renal function, usually caused, in children and teenagers, by an...