We wished to assess the efficacy of inhaled salmeterol (SML; 50 micrograms b.i.d.) compared to a combination of slow-release theophylline and ketotifen p.o. (TK; T 300 mg+K 1 mg b.i.d.) for the treatment of nocturnal asthma. Ninety six patients with nocturnal asthma, (forced expiratory volume in one second (FEV1) 60-90% of predicted value, reversibility > or = 15%, at least two nocturnal awaken...

The treatment preferences of 109 general practitioners (GPs) for childhood asthma were determined. Availability and adherence to clinical practice guidelines (CPG) for the treatment of childhood asthma was also assessed. Ninety eight (90%), 60 (55%) and 33 (30%) GPs considered nocturnal symptoms > 2 times/week, exercise induced wheeze and cough respectively as indications for preventer therapy....

Melkersson – Rosenthal syndrome (SMR) is a disease manifested by triad of symptoms: swelling the lips and/or face, paralysis facial nerve, scrotal tongue. In clinical practice, monosymptomatic variant SMR more common. The can develop at any age, but most cases occur 25–40 years with 2-fold predominance women among patients. children, often observed age 7 to 12 years, and smallest child describe...