PURPOSE To evaluate the safety and efficacy of corneal collagen crosslinking (CXL) for the treatment of progressive keratoconus. DESIGN Prospective, randomized, multicenter, controlled clinical trial. PARTICIPANTS Patients with progressive keratoconus (n = 205). METHODS The treatment group underwent standard CXL and the sham control group received riboflavin alone without removal of the e...

purpose: to evaluate the safety, efficacy, stability and predictability of posterior chamber collagen copolymer phakic intraocular lens (piol) implantation to correct myopia and myopic astigmatism in keratoconus-affected patients. methods: uncorrected (ucva) and best-corrected (bcva) distance visual acuity, refraction and complications were evaluated in 22 keratoconic eyes of 14 patients who un...

purpose: to compare corneal hysteresis and resistance factor after penetrating keratoplasty (pk) and deep anterior lamellar keratoplasty (dalk) using anwar’s big-bubble technique using the ocular response analyzer. methods: forty-five pk eyes and 23 dalk eyes with keratoconus were compared in terms of corneal hysteresis (ch), corneal resistance factor (crf), goldmann-correlated intraocular pres...

purpose: to determine the effect of retained donor descemet membranes (dms) on visual outcomes following deep anterior lamellar keratoplasty (dalk). methods: in this retrospective comparative study, keratoconic eyes undergoing dalk using the big-bubble technique were enrolled. a bared dm was achieved in all cases. a donor cornea without (group 1; 48 eyes) or with (group 2; 22 eyes) dm was sutur...

PURPOSE To evaluate by vector analysis the corneal astigmatic changes occurring in keratoconic corneas during a 3-year follow-up and to determine the relationship between these changes and other clinical changes. METHODS Keratoconic eyes (n = 114) of 75 patients ranging in age from 14 to 70 years were retrospectively reviewed in four different centers. In all cases, a 3-year follow-up was com...

Custom high-resolution high-speed anterior segment spectral domain Optical Coherence Tomography (OCT) was used to characterize three-dimensionally (3-D) corneal topography in keratoconus before and after implantation of intracorneal ring segments (ICRS). Previously described acquisition protocols were followed to minimize the impact of the motions of the eye. The collected set of images was cor...

PURPOSE To compare complete versus incomplete ring implantation for keratoconus correction. METHODS We investigated 25 eyes of keratoconic patients, of which 15 had femtosecond-assisted MyoRing corneal implantation (Group 1) and 10 had femtosecond-assisted Keraring segments (Group 2). Uncorrected distance visual acuity (UCVA), best corrected distance visual acuity (BCVA), mean K (K m), sphere...

PURPOSE To compare the corneal volume in keratoconic and normal eyes to improve our understanding of the tissue distribution associated with the disease. MATERIALS AND METHOD The Oculus Pentacam tomographer (Oculus Inc., Wetzlar, Germany) was used to analyze the corneal volume contained within discs with diameters of 3, 5, 7, and 10 mm in 21 patients with keratoconus and 21 matched healthy co...