Background The most recent update of the Global Burden Disease figures (GBD 2013) estimated that 242 million people were living in world with symptomatic and activity-limiting OA hip and/or knee. Many potential disease-modifying osteoarthritis drugs (DMOADs) have been investigated, but to date no DMOADs slow or stop disease progression approved by Food Drug Administration (FDA) European Medicin...

Abstract Background Pain in osteoarthritis (OA) has been attributed traditionally to local tissue injury causing ‘nociceptive pain’. However, recent studies suggest that neuropathic and central sensitization mechanisms may contribute the pain experience. relationship between these physical function not thoroughly addressed. This study aimed assess association of with knee OA. Results Participan...

Objective To examine the associations of knee injury, radiographic osteoarthritis severity, and quadriceps strength with pain exacerbation during walking. Design Within-person knee-matched case-control study. Methods Participants from Osteoarthritis Initiative who completed a 20-m walking test at 24-month visit were included. Pain was defined as an increase in intensity 1 or more on numeric rat...

Osteoarthritis is the most common joint disorder, with a prevalence that increases with age. In 80 year old women radiologically defined osteoarthritis is found in over 70% in the distal interphalangeal joints (DIP) and in approximately 50% in the knees.' Osteoarthritis is characterised by pain on movement, and the pathophysiological processes can be visualised radiologically. Radiographic find...

Amaç:Osteoartrit, çoğunlukla dizleri etkileyen en yaygın eklem hastalığıdır. Son yıllarda, düşük dereceli kronik inflamasyonla seyreden multifaktöriyel bir hastalığın osteoartrit patogenezinde rol oynadığı düşünülmektedir. Bu çalışmanın amacı diz osteoartriti olan hastalarda radyolojik evreleri ve hastanın günlük yaşam aktivite düzeyleri ile serum kıkırdak oligomerik matriks proteini (COMP) met...

Background: At present, there is a growing trend towards osteoarthritis spreading among the population of Russia and entire world, therefore, search for an effective low-traumatic method pain syndrome relief in coxarthrosis important problem modern medicine.
 Clinical case description: A clinical treatment 64-year-old patient, working pensioner, with complaints severe left hip joint pictur...

Mục đích: Đánh giá kết quả dựa trên siêu âm và cộng hưởng từ của liệu pháp điều trị thoái hóa khớp gối bằng huyết tương giàu tiểu cầu phối hợp với tế bào gốc trung mô mỡ tự thân”. Đối tượng phương pháp. 30 bệnh nhân, 26 nữ, 4 nam, tuổi bình 58,63 ± 11.11, thời gian mắc 5,3± 4,6 năm ứng 60 được chẩn đoán giai đoạn II – III theo phân loại của Kellgren và Lawrence. Sau khi chụp tất cả nhân đều tiế...

Objective: To explore the relationship between pain, functional impairment (disability) and radiographic findings in patients with osteoarthritis of knee. Study Design: Cross sectional study Place Duration Study: Department Rhematology, Pakistan Air Force Hospital Islamabad from 1st September 2020 to 28th February 2021 Methodology: One hundred thirty eight knee joint were included. Weight beari...

Background Pain in knee osteoarthritis remains the main symptomatology, classically considered as nociceptive. A neuropathic component of this pain has recently been described. The identification which is essential for adequate management. Objectives objective our study to evaluate relationship between prevalence and stages radiographic severity gonarthrosis. Methods This a descriptive cross-se...