PURPOSE To assess the anterior segment parameters of keratoconus (KC) eyes at different stages of the disease by a new Scheimpflug camera combined with Placido disk corneal topography (Sirius, CSO, Italy) in a sample of the Iranian population. METHODS A total of 225 eyes of 225 individuals comprising 41 suspect KC, 40 mild KC, 71 moderate KC, 48 severe KC and 25 normal eyes were assessed for ...

The severity of corneal inflammation depends on the activity of infiltrating neutrophils responding to chemotactic factors such as CXC chemokines. This study examines the relative contribution of CXCL1/keratinocyte-derived chemokine (KC), CXCL2/MIP-2, and CXCL5/LPS-induced chemokine (LIX) in neutrophil recruitment to the corneal stroma during LPS keratitis, where neutrophils infiltrate the corn...

OBJECTIVE As compared to knee chondrocytes (KC), talar chondrocytes (TC) have superior synthetic activity and increased resistance to catabolic stimuli. We investigated whether these properties are maintained after TC are isolated and expanded in vitro. METHODS Human TC and KC from 10 cadavers were expanded in monolayer and then cultured in pellets for 3 and 14 days or in hyaluronan meshes (H...

Keratoconus (KC) is a bilateral degenerative disease of the cornea characterized by corneal bulging, stromal thinning, and scarring. The etiology of the disease is unknown. In this study, we identified a new biomarker for KC that is present in vivo and in vitro. In vivo, tear samples were collected from age-matched controls with no eye disease (n = 36) and KC diagnosed subjects (n = 17). Sample...

The purpose of this study was to measure daily and seasonal evapotranspiration and daily crop coefficient of two common varieties of sunflower (Sirna and Euroflor) via drip-tape irrigation system. For this purpose, the sunflower water use was determined by daily monitoring of soil moisture at the depths of 10, 20, 30, 40 and 60 cm, and the crop evapotranspiration (ETC) was measured using volume...

Undetected subclinical keratoconus (KC) is the main risk factor for iatrogenic ectasia. Many parameters have been proposed to help differentiate normal from subclinical KC corneas. Linear discriminant analysis is a technique that models the difference between different classes of data by looking for linear combinations of variables which best explain the data. The association of surfaces elevat...

We establish a computational approach to extract the bending modulus, KC , for lipid membranes from relatively small-scale molecular simulations. Fluctuations in the splay of individual pairs of lipids faithfully inform on KC in multicomponent membranes over a large range of rigidities in different thermodynamic phases. Predictions are validated by experiments even where the standard spectral a...

Let G be a connected, linear semisimple Lie group with Lie algebra g, and let KC → Aut(pC ) be the complexified isotropy representation at the identity coset of the corresponding symmetric space. The Kostant-Sekiguchi correspondence is a bijection between the nilpotent KC -orbits in pC and the nilpotent G-orbits in g. We show that this correspondence associates each spherical nilpotent KC -orbi...

BACKGROUND/AIM The generation of reactive oxygen species by activated Kupffer cells (KC) may contribute to reperfusion injury of the liver during liver transplantation or resection. The aim of our present studies was to investigate (1) prevention of hepatic reperfusion injury after warm ischemia by administration of the antioxidant glutathione (GSH) and (2) whether GSH confers protection throug...

BACKGROUND Inflammatory processes play important roles in both neuropathic and inflammatory pain states, but the effects of inflammation per se within the sensory ganglia are not well understood. The cytokine growth-related oncogene (GRO/KC; CXCL1) shows strong, rapid upregulation in dorsal root ganglion (DRG) in both nerve injury and inflammatory pain models. We examined the direct effects of ...