Han, Bing, Baoan Ji, and Craig D. Logsdon. CCK independently activates intracellular trypsinogen and NF-kB in rat pancreatic acinar cells. Am J Physiol Cell Physiol 49: C465–C472, 2001.—In the cholecystokinin (CCK) hyperstimulation model of acute pancreatitis, two early intracellular events, activation of trypsinogen and activation of nuclear factor-kB (NF-kB), are thought to be important in th...

The biological action of luteinizing hormone/human chorionic gonadotropin (lutropin/choriogonadotropin) in the ovary is mediated by interaction with its specific receptor. Lutropin/choriogonadotropin-receptor hnRNA is processed into multiple mRNAs. However, nucleotide sequences for many of the transcripts, including the major form (6.7 kb), have yet to be determined. In an attempt to identify a...

In normal cells exposed to stress, the central transcription factor NF-kB is activated only transiently, to modulate the activation of downstream immune responses. However, in most cancers, NFkB is abnormally activated constitutively, contributing thus to oncogenesis and tumor progression. Therefore, downregulating NF-kBactivity is an important goal of cancer treatment. In order to control NF-k...

background: limited resources for adult stem cells necessitate their in vitro culture prior to clinical use. investigating mitochondrial dna (mtdna) and telomere shortening has proved to be important indications of stem cell validity. this study was designed to investigate these indicators in multiple passages of three adult stem cell lines which were produced in our stem cell laboratory. metho...

fusarium wilt of chickpea, caused by f. oxysporum f. sp. ciceris, is one of the most important diseases of this plant in iran. in order to control this disease, fluorescent pseudomonads were isolated from the rhizosphere of chickpea plants in khorasan province by using king,s b medium (kb). antifungal activity of 80 bacterial strains against f. oxysporum f. sp. ciceris was evaluated on kb and p...

Kontrasepsi adalah upaya untuk mencegah terjadinya kehamilan. Implant salah satu jenis kontrasepsi yang berupa susuk terbuat dari sejenis karet silastik berisi hormon, dipasang pada lengan atas. dapat digunakan jangka panjang 5 tahun dan bersifat seversible. Berat badan parameter antropometri sangat labil. Siklus menstruasi proses perubahan hormon terus-menerus mengarah pembentukan endometrium,...