lamin gene (Lmna) develop an EDMD-like syndrome soon after birth and die within 6 weeks of cardiovascular disease. A recent publication by Chen et al. (2012) reports the remarkable finding that downregulation of Sun1 expression in Lmnadeficient mice significantly extended their life span along with amelioration of cardiac pathology. Thus, LINC complexes could represent viable therapeutic target...

The linker of nucleoskeleton and cytoskeleton (LINC) complex, composed of outer and inner nuclear membrane Klarsicht, ANC-1, and Syne homology (KASH) and Sad1 and UNC-84 (SUN) proteins, respectively, connects the nucleus to cytoskeletal filaments and performs diverse functions including nuclear positioning, mechanotransduction, and meiotic chromosome movements. Recent studies have shed light on...

Genome haploidization during meiosis depends on recognition and association of parental homologous chromosomes. The C. elegans SUN/KASH domain proteins Matefin/SUN-1 and ZYG-12 have a conserved role in this process. They bridge the nuclear envelope, connecting the cytoplasm and the nucleoplasm to transmit forces that allow chromosome movement and homolog pairing and prevent nonhomologous synaps...

In this paper, we study some ring theoretic properties of the amalgamated duplication ring $Rbowtie I$ of a commutative Noetherian ring $R$ along an ideal $I$ of $R$ which was introduced by D'Anna and Fontana. Indeed, it is determined that when $Rbowtie I$ satisfies Serre's conditions $(R_n)$ and $(S_n)$, and when is a normal ring, a generalized Cohen-Macaulay ring and finally a filter ring.

Let R be an associative ring with unity. An element a in R is said to be r-clean if a = e+r, where e is an idempotent and r is a regular (von Neumann) element in R. If every element of R is r-clean, then R is called an r-clean ring. In this paper, we prove that the concepts of clean ring and r-clean ring are equivalent for abelian rings. Further we prove that if 0 and 1 are the only idempotents...

In the combination of 5-fluorophenyl-1, 3, 7, 9-tetra methylpyrido [2, 3, d, d, 5, 6 dipyrimidine -2, 4, 6, and 8 tetron, there are 4 rings, respectively, ring that is attached to the halogen ring A and, respectively, a ring The lower and the right to the left of the ring A are called C, B, and D. Calculations and studies show that the amount of aromatics in halogen-ring A in all cases has the ...

the author studies the $bf r$$g$-module $a$ such that $bf r$ is an associative ring‎, ‎a group $g$ has infinite section $p$-rank (or infinite 0-rank)‎, ‎$c_{g}(a)=1$‎, ‎and for every‎ ‎proper subgroup $h$ of infinite section $p$-rank (or infinite 0-rank respectively) the quotient module $a/c_{a}(h)$ is‎ ‎a finite $bf r$-module‎. ‎it is proved that if the group $g$ under‎ ‎consideration is local...

⁎ Corresponding author. Tel.: +1 662 915 1523. E-mail addresses: [email protected] (S. Kash [email protected] (V. Mahajan). 1 Tel.: +1 512 471 0840. 2 This definition has been used in several recent academ Anderson & Reeb (2003); Anderson,Mansi, and Reeb (200 Ali, Chen, and Radhakrishnan (2007); and Kashmiri a searchers, however, have used a threshold level of famil firm....

An R-module M is called epi-retractable if every submodule of MR is a homomorphic image of M. It is shown that if R is a right perfect ring, then every projective slightly compressible module MR is epi-retractable. If R is a Noetherian ring, then every epi-retractable right R-module has direct sum of uniform submodules. If endomorphism ring of a module MR is von-Neumann regular, then M is semi-...