There were substantiated the expediency of the using for the determination of identity of Cassia acutifolia Del. leaves of spectrophotometry and TLC. As the results of the chemical study of Cassia acutifolia leaves there were isolated the predominant components of this plant 1,7-dihydroxy-3carboxyanhraquinone, 8-O-β-D-glucopyranoside of torachrysone, kaempferol-3-O-gentiobioside and on this bas...

synthesis of some new monocyclic β-lactams containing a quaternary carbon center via a [2+2]cycloaddition reaction is described. the reaction of achiral diphenyl ketene with chiral aldimines derivedfrom chiral 2, 3, 4, 6-tetra-o-acetyl-β-d-galactopyranosylamine, 2, 3, 4, 6-tetra-o-acetyl-β-dglucopyranosylamine and different benzaldehydes resulted in the formation of β-lactams as singlediastereo...

Background and objectives: Plumeria rubra L. (Apocynaceae) is a deciduous shrub or small tree cultivated in subtropical and tropical countries.  Its bark is prescribed to treat amoebic dysentery,   dropsy, jaundice, scabies, gonorrhea, venereal affections and wounds. In the present research, we aimed to isolate and identify the chemical constituents of the bark of ...

In this study, the anti-adipogenetic activity of 300 plant extracts was investigated using an Oil Red O staining assay in a 3T3-L1 cell line. Our results indicate that three plants, including the stem and leaf of Physalis angulata, the whole grass of Solidago virgaurea, and the root of Dioscorea nipponica, produced over 90% inhibition of adipogenesis. Kaempferol-3-O-rutinoside, which demonstrat...

An amino acid derivative, L-(-)-(N-trans-cinnamoyl)-arginine, was isolated from the whole plant of Glinus oppositifolius (L.) Aug. DC. along with kaempferol 3-O-galactopyranoside, isorhamnetin 3-O-beta-D-xylopyranosyl-(1-->2)-beta-D-galactopyranoside, vitexin, vicenin-2, adenosine and L-phenylalanine. The structure determinations were based on analyses of chemical and spectroscopic methods.

Clusia nemorosa has been widely used in folk medicine to treat various ailments, including headaches and inflammation. Investigation of the fruits of Clusia nemorosa (Clusiaceae) led to the isolation and characterization of a new phloroglucinol derivative, named 6S,8S,28S-nemorosic acid (1), together with seven known compounds: friedelin (2), β-sitosterol (3), stigmasterol (4), β-sitosterol gly...

Three flavonol triglycosides kaempferol 3-[2Gal-(4-acetylrhamnosyl)robinobioside], kaempferol 3-(2Gal-rhamnosylrobinobioside) and quercetin 3-(2G-rhamnosylrutinoside) have been isolated from a methanolic extract of Galega officinalis aerial parts. They are reported for the first time in the genus Galega; moreover, the acetylated triglycoside is a new natural product.

In the course of search for potent inhibitors of chitin synthase II from natural resources, seven tannins and related compounds were isolated from the aerial part of Euphorbia pekinensis and identified as gallic acid (1), methyl gallate (2), 3-O-galloyl-(-)-shikimic acid (3), corilagin (4), geraniin (5), quercetin-3-O-(2"-O-galloyl)-beta-D-glucoside (6), and kaempferol-3-O-(2"-O-galloyl)-beta-D...

Four known flavonoids: quercetin 3-O-β-D-rutinoside (Q3Rut), myricetin 3-O-β-D-galactopyranoside (M3Gal), quercetin 3-O-β-D-galactopyranoside (Q3Gal) and quercetin 3-O-β-D-glucopyranoside (Q3Glc), for the first time were isolated from aerial parts of Euphorbia microsciadia. The chemical structure of them was elucidated on the basis of 1 and 2 D-NMR spectra and different spectroscopic techniques...

Retinoblastoma is a pediatric retinal tumor caused by mutational inactivation of the tumor suppressor pRb, and the present study aims to examine the role of kaempferol in retinoblastoma and explore its underlying molecular mechanisms. The mRNA and protein expression levels were measured by quantitative real time PCR (qRT-PCR) and western blot, respectively; cell growth and invasion was determin...